ID   A0A3S3E2W6_9NOCA        Unreviewed;       351 AA.
AC   A0A3S3E2W6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=NAD-dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:RVW04086.1};
GN   ORFNames=EGT50_06270 {ECO:0000313|EMBL:RVW04086.1};
OS   Rhodococcus xishaensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=2487364 {ECO:0000313|EMBL:RVW04086.1, ECO:0000313|Proteomes:UP000283479};
RN   [1] {ECO:0000313|EMBL:RVW04086.1, ECO:0000313|Proteomes:UP000283479}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW51113 {ECO:0000313|EMBL:RVW04086.1,
RC   ECO:0000313|Proteomes:UP000283479};
RA   Li L., Lin H.W.;
RT   "Rhodococcus spongicola sp. nov. and Rhodococcus xishaensis sp. nov. from
RT   marine sponges.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RVW04086.1}.
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DR   EMBL; RKLO01000002; RVW04086.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3E2W6; -.
DR   OrthoDB; 3174087at2; -.
DR   Proteomes; UP000283479; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000283479}.
FT   DOMAIN          4..263
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   351 AA;  37804 MW;  1D39360B7D55630F CRC64;
     MKILVTGASG FLGGRLARRL ADDGDWDVSI LVRPTSRLVD LGDLSGMRIL YGDLTDSASL
     EAATLGVDVV VHSAARVDER GTRAQFEREN VDATRVLLDA AKANGASRFV FISSPSALMS
     YDGGDQINLD ESAPYPTRFL NLYSETKAAA EQLVLAANGD GFTTCALRPR AIWGPGDRSG
     PIVRLLGRAR AGKLPNLSGG RDVYASLCHI DNIVDATIKA ARSDSAAGEA IGGKAYFIAD
     AEITNIWPYM AEVAKEFGFT LPDKSVNPRV VSAIVKVLDR VWTLPYLAAR YSPPLSMYVL
     ALMTRSATFD TSAAERDFGY TPVVDRATGM RQFREWVDSQ GGLAELTRDL A
//