ID   A0A3S3NVY0_9ACAR        Unreviewed;       874 AA.
AC   A0A3S3NVY0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|ARBA:ARBA00017947};
DE   Flags: Fragment;
GN   ORFNames=B4U79_05225 {ECO:0000313|EMBL:RWS08424.1}, B4U79_15416
GN   {ECO:0000313|EMBL:RWS10192.1};
OS   Dinothrombium tinctorium.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC   Trombidioidea; Trombidiidae; Dinothrombium.
OX   NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS10192.1, ECO:0000313|Proteomes:UP000285301};
RN   [1] {ECO:0000313|EMBL:RWS10192.1, ECO:0000313|Proteomes:UP000285301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS10192.1};
RA   Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA   Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT   "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT   transferred genes associated with secondary metabolism.";
RL   Gigascience 0:0-0(2018).
RN   [2] {ECO:0000313|EMBL:RWS10192.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS10192.1};
RA   Dong X.;
RT   "Trombidioid mite genomics.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VPS16 family.
CC       {ECO:0000256|ARBA:ARBA00009250}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWS10192.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NCKU01002979; RWS08424.1; -; Genomic_DNA.
DR   EMBL; NCKU01002190; RWS10192.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3NVY0; -.
DR   STRING; 1965070.A0A3S3NVY0; -.
DR   Proteomes; UP000285301; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   InterPro; IPR016534; VPS16.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   InterPro; IPR006926; Vps16_N.
DR   PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR   PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 1.
DR   Pfam; PF04841; Vps16_N; 1.
DR   PIRSF; PIRSF007949; VPS16; 1.
DR   SUPFAM; SSF117289; Nucleoporin domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          90..455
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          554..859
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RWS10192.1"
SQ   SEQUENCE   874 AA;  101600 MW;  97E74A0C3F22ECAF CRC64;
     VMALYTGSWN PLGNVAFYRK FELYSMQWKD DVNVNLNECF VAASSFSGCI VRDGTSKELS
     KAVTVYFDIS ELFVFYSFVI YFLPFTATLK KERKNQKDLN AKSFLSVYTA CGYLISSFKL
     PFDNLTYFGW SIDEELICVQ EDGTVTFYDI FLALQDSLIL HEEIRDTRVH ECRLFHHDHV
     TGIAAVTFAN KILVVNNIKD PKARYFPVIP GVEPTKSAWN VIACDGKETQ IILATENNRL
     FLINATNFIE LDYRIAKPFD FITNISTSFD GKKLAFLTNT GVLWIGFLYE KDLKKNCEFE
     TKSKTKPQFM MWCGEDAVAC LWKNILLLVG KEKEWLNFVI EPPVHLVEEI DGIRIIGNDV
     HEFLQQVPEV VVDVFRIGSV SAGALLLEAS KEFQKRTHKA DEYMKMLSDR HEVELAVRQC
     VETAGHEYTV STQKMLLRAA SFGKCFVPET DPKFFVSMCQ TLRVLNAIRN PNIGIPMTYN
     QLQYLSIDVV IQKLVLRHHY FIAIKIAKFL KIPEERGVMR ILSNWAYYKV RQVQLDDEQV
     AREIAEKLGY TTGISYSDIA CKAIDFGRTH LAIKLLDHEL KATQQVPLLL KLKQYQMAMK
     RADESGDMDL IYTCIIMMKN ILPSRDFLMI VRNYPVAYSL YQKYCKQENF EKLKDLYNQE
     DDFNAQAYCW ILESYKSENI ATRQDCLRSA AESFRKAKHD FMSSETDEQI KLLKYQSTME
     EKFHHQKFVD LSVHQTIKKL LQEGEYKLAE ELKKDRKVPD KRFWWLKITV LAEQGQWLEL
     EKFSKVKKSP IGYEPFVDIC LKHKNKFEAQ KYVPKVKEEN KVRYHVKTGQ LEEAAKIAFD
     EKDVEALEFI QSKCSTNRPL KERVEAMKLQ LTRR
//