ID A0A3S3P5P9_9ACAR Unreviewed; 2388 AA.
AC A0A3S3P5P9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
DE Flags: Fragment;
GN ORFNames=B4U79_04450 {ECO:0000313|EMBL:RWS08784.1}, B4U79_04692
GN {ECO:0000313|EMBL:RWS08431.1}, B4U79_05434
GN {ECO:0000313|EMBL:RWS08558.1}, B4U79_06800
GN {ECO:0000313|EMBL:RWS08194.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS08558.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS08558.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS08558.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:RWS08558.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS08558.1};
RA Dong X.;
RT "Trombidioid mite genomics.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS08558.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NCKU01003090; RWS08194.1; -; Genomic_DNA.
DR EMBL; NCKU01002973; RWS08431.1; -; Genomic_DNA.
DR EMBL; NCKU01002913; RWS08558.1; -; Genomic_DNA.
DR EMBL; NCKU01002786; RWS08784.1; -; Genomic_DNA.
DR STRING; 1965070.A0A3S3P5P9; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd13953; 7tm_classC_mGluR-like; 1.
DR Gene3D; 3.40.50.2300; -; 8.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 4.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 4.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..2388
FT /note="G-protein coupled receptors family 3 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033399021"
FT TRANSMEM 2026..2047
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2059..2079
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2091..2109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2130..2154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2181..2201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2213..2233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2245..2268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2052..2271
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 2321..2341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RWS08558.1"
SQ SEQUENCE 2388 AA; 268326 MW; 4BF70562F7FFC1C3 CRC64;
RYWLRYVPVV IAALTAKVMC IDTTTQTYCA SNKFKNDVSI IEENADILIG ALLNVHELGS
KGLFDCGNIT RQGITTYEAL EWVIEVINQQ NGVINGSPIK DSFIPGVKLG AKVFDTCFHQ
EMSIRHLTEL YPILESGTNT CGSETSPELH TIGVLDATGL SVDSRVTEYS HINFIPLVSL
SHTSAIPPDT MGKILAQILH DLEWIQIALI HETDEHSVHV VKLLGQVAMT HKICLNVVES
LPTVEETTSS QELRSTALAF NSVTSSIAEN TPILVIGNGK SIHKLVDVML ENAEIALKYQ
WFFASLPDPE TIKSLAAKLN EKLFTLATYP ASISMFEAFW QNLQSPNKQQ RIWFDEFVEL
TKKCDATSCF NKLLPEGPID VLWRTHYSLP AIHAVFTFAH ALRNAWNDKC KSIPGFCSTL
RNLSRKDFVT LYLEPFQFEH NTSHRSPPEI AGRKSEHSRA GEIEGLHLAI TNFEFNGKGD
VNYKQLIVYD SASDNAKVID ENFKFRSSPC PLTGCQKCVK VRQSRVELIK KDPLINSADE
PVETYQVPSE AANIVIPIVL PIHRVGKSPL ECSNDINAAA IYDFEAALWM IDQINSDKEF
VPGVKFGAIV LDSCSSSLKA IERVSKFLTQ KIDSVLGTVS IENALSAITS SSTQEIKPTV
QLLSSLNITV VSAQDLTPTG LTLGSSHHRL QTTLTYRHFI HATIEQLKYF DWNYVSLVMT
KENEESVAMT NFFKEIAAEN GICISTILAI DELDFFASSQ SAILNLKQAK DFGAKVVLLM
TTFDSTRALI TTFNKFVRGG NLHSNEFQWI LVRESNLNIV NSLEFEMIGS LALREGQGSI
KTFIEYFGQL NPETNTRNPW FKEFWLQTTS CRTDDCLIRQ MNPISTINVM QSVLAIISGF
ARLRNEVCGN QSGICQKLRS KPDIRSRISS YIQFTAAVFT TPVSKDIGEM FSFTKDGFGM
KSIDVLNFKK DTSTKFFRFD QVAVYDQVFR KLENRVYVSY DDMGNEMPTE KLKSECILTE
CSITCHEKNV DFLRIESSDN LYISASIGVH QQSSSNPLQC GPISLSSGIQ NLEAFLWALD
TVNNHPSILP GVQLGAFILD SCSSHQKTAR DVSNFLSNSA VSNQKRNINT PLPKDIVGFI
VDSDNVKIVD AVVDVTLPLG IMTIAAHNRN SKYDEPDFSK LLRLVLSNQV YADSIISILL
HFGWNFVSVL YEDDKASIIN TFNNFKSKSK IFGIEFALEE KIMPQSNINF MTSVVNRLQK
KAKLGSHVVI LFLNENQIAY LLDAVKKIQN DNQSSYGEFV WLAIDGKDAF HTYPRTSLGA
LSISPPLSSV PNFRNYFTHL QLRNNSRNPW FGEYWQKIHN CKGITCYENI DPTNIEKSII
NDRETLAVIN SVFAIAHGME LARRALCPQA TKGLCLEMKE HPKLGDVVFD YVKRSVFLGA
EGKKVQFSEN ANYIVGNLNI YNLRHVSSKA AAFLNVGRFN EKEGLFINTS KAVSYNENGD
EISFRDIVSR CNDQQKCRHL GGTLSRSDSA PVLQMIPSHS FTIGALLPLH KPGKSFFSCG
ELDVEMMFQN LIAFNFAIDK INSNKTVLGD TKVGAIAFDY CGRKEKAEEK LFTYLSEANL
ETIKVPPKSL IALITYSDET ASEVDPILSS FKITHLTIPA LSSSSFNEAK SNPSSRILRS
VPSKYNQIEA IIDILLEFEW KFVNIIYDDL NLKKKFRQKS AASKICVDET IDLSEYDENS
TVISQRFGNG FNQKSEAKVI VSLLNSQMNK LMFASLKMDK LQSFVWIGNE DIIEAANEIQ
IPIKVIAVKV ESYSNEEFKK YFSSLSLGHY GAVPMSWFEE FWQTYFKCQL PNSLVVQNQF
SAICSGQERI DASQVLENEF VQHTITSILA IAKGTENYLK KHCVPGSLLS SIDDCADNAR
EILYEEIRNA LIDNESSDNE ISNTMQTPYG FHVLTKFSNK PFSNSGVWKN GILNLVWKNT
LQKELGIDFK SICTTKCSKC WEQFKSEQLT GVKPHMMANF KQPSGMIVSI LSGIGVLAVL
ICGLYFLMVF PISVGTTVLG YTILIGLFIL YSINFLFLMP VDFSVCWLRR FGMSLAYSIV
ISGMLVKVMN TWRLMAFRNA RPDELRLTSC CGLVFISGGL IALQIIVTIV WLFLYPPKPV
FNDIWSCSQN SSNFVVETES VVSLLYILLL LVITIFFSAL TWKSYDNNYE PRYIMFCCSL
MGIMWALWSV FSSYLTNSFH LTREMTVICV NLINATVIMI FLFLRKLYIY MKLTRKIRND
RDYKARLQPS SFPGSMYGTV HKTNPIIWES QHTVYSKRSA TRPPFESDQV DDNASSCGST
TGSVQVQAQD LYPMEVYDGG SQFQAMSSLF NANSNRSVYL MDESTYIR
//
