ID A0A3S3PBY8_9ACAR Unreviewed; 391 AA.
AC A0A3S3PBY8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Spermine synthase-like isoform X1 {ECO:0000313|EMBL:RWS16445.1};
GN ORFNames=B4U79_03889 {ECO:0000313|EMBL:RWS16449.1}, B4U79_05732
GN {ECO:0000313|EMBL:RWS08369.1}, B4U79_10077
GN {ECO:0000313|EMBL:RWS16445.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS16445.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS16445.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS16445.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:RWS16445.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS16445.1};
RA Dong X.;
RT "Trombidioid mite genomics.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS16445.1}.
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DR EMBL; NCKU01003001; RWS08369.1; -; Genomic_DNA.
DR EMBL; NCKU01000230; RWS16445.1; -; Genomic_DNA.
DR EMBL; NCKU01000229; RWS16449.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3PBY8; -.
DR STRING; 1965070.A0A3S3PBY8; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0016768; F:spermine synthase activity; IEA:InterPro.
DR GO; GO:0006597; P:spermine biosynthetic process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00198; Spermidine_synth; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001045; Spermi_synthase.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR InterPro; IPR015576; Spermine_synthase_animal.
DR PANTHER; PTHR46315; SPERMINE SYNTHASE; 1.
DR PANTHER; PTHR46315:SF1; SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 146..388
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 301
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 391 AA; 44042 MW; 7268BA8C012E7345 CRC64;
MSEHKAFTCL MSIDGDFLPN SHSLDSSVET VKRTLRSMFA LNSEFDIPVG NGLLCVLSSN
AENTVNTSLT VTIRLHRNQN FVSINIDSCE PLIPADCNTL EANDLRGLEA ISLSNNTMDK
LRRQLSDALG IEVEKIPVLK RGLAVPNYFS SSDERVLEYD FEKILFNKRS SFQHIRILHS
KTLGNALLLD DLQNLADSDI AYTHSLMKYG EICYEGKEVL ILGGGDGALL HELLKEKPKF
VLMVDIDEMV IESCREHLRA SCGQVLDTLK SDNYEIIIGD CVKYLEEFAA ENRKFDVIFN
DLTDIPISTT ADASKHLWDF VKKILNLSLR CLRDDGKYLN HATGAGSIKA LETFEKLLTE
LPVKVKFSRH SAYVPSFLEN WVFYEISKCN E
//
