ID A0A3S3PHD4_9ACAR Unreviewed; 634 AA.
AC A0A3S3PHD4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE SubName: Full=Transmembrane and coiled-coil domain-containing protein-like protein {ECO:0000313|EMBL:RWS12454.1};
GN ORFNames=B4U79_07559 {ECO:0000313|EMBL:RWS12442.1}, B4U79_11705
GN {ECO:0000313|EMBL:RWS12454.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS12454.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS12454.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS12454.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:RWS12454.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS12454.1};
RA Dong X.;
RT "Trombidioid mite genomics.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS12454.1}.
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DR EMBL; NCKU01001318; RWS12442.1; -; Genomic_DNA.
DR EMBL; NCKU01001316; RWS12454.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3PHD4; -.
DR STRING; 1965070.A0A3S3PHD4; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 193..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 634 AA; 69172 MW; 45A84B4BE210A112 CRC64;
MDASTEQHDD ALSTPGSIGY NSISSIGSDS IEPLSSSLSL AGNYSLCGIC ALSFHYLFDD
TSNRQFCETT INCLVNHLSL PKQVANAMQA LLNGEGGDIQ AFINLLKEEA SLKNSCVRVV
EELVMFSVRE GVYDARLRIL ILYVAELLRV PLPLVELYEE SVVEMLSSDI PEQTNEELIE
KAKRQRNKKI KRYFMIGLAG LGGGAIIGLT GGLAAPFVAA GAGAIIGGAG AAALGSTAGI
AVIGSLFGVA GAGLTGYKMK KRVGDIEEFA FDTLTKGREL HLTIAVSGWI TEEDVNAFQK
PWQSLMNSRE QYCIRYESSY LLELGRAMDY FLSFAVSMAA QEALKYTILS GIITAIAWPA
TFVTFASVID NPWGVCIRRS AEVGKHLAEI LIARQQGKRP VTLIGFSLGA RVIFYCLQEM
AQRKGCEGIV EDVVLLGAPV PGYVDQWKSF QRVVNGRIVN GYCKGDWLLK FLYRTSTATL
KIAGLGPVEW KDRRMINIDL SEIVSGHMDY YAKMPLVLEA VGVRTNEDLT KRDAKTMRKC
FSGLPHTVEK SSSSFTINSS LRLSKSETNF SRRFSSPCYI GEEVSVNIPR RSSSLESVLS
KISSGVAMTP SISHSDNLSH KLSKSLSFQK PLDP
//
