ID A0A3S3PK78_9ACAR Unreviewed; 1172 AA.
AC A0A3S3PK78;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Hemicentin-1-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B4U79_12939 {ECO:0000313|EMBL:RWS14198.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS14198.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS14198.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS14198.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS14198.1}.
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DR EMBL; NCKU01000778; RWS14198.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3PK78; -.
DR STRING; 1965070.A0A3S3PK78; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF164; MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 5.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 7.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 924..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..127
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 138..230
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 235..319
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 324..403
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 418..502
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 507..617
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 620..718
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 724..816
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 956..1031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 131375 MW; C19DA5FD2BDC694F CRC64;
MALHSDRELR ANKDISTTTI AQSSRPGVVR DALEDDTIHL ECRFNPNQIS KNENEYVFYW
KKTNNIDQDV VTVNHNTLVK GYSLMYSIRE GKYDLVISAA KYERDNGKFE CKIKENGSGR
EVENAVYTLT ILIPPGPPQI HPANPVAKEG EPFQLTCSSV GGSPDPIINW YKDDFPLEAE
IEKGGSKDKP TKSILTINPT INDNRAVYKC VVWNRAVREE GKKEDTVLLT VHYVPRVKVG
PANPLNVLVG SDATMNCVVD ANPPAKKINW FKNDRILSHK ANHTIVGVMP TDSGLYSCIA
DNGIKGPDGS PGRGDLELSV QFDPTVTVIN EEEAVIGESV TVKCNVHSNP KPHTIIWTKD
ANPQVIQEGD VLRLERISAA DSGRYTCTAT NTLRPTGNHV TLERSGNASV NIRVKHRPGN
TEILPANPIA VSGKPFTLSC IAKPPGWPVP EYKWWREGQH KEELGRQQNY TFISIHVRNE
GNYYCQPYNA LGTGSVSSVY LTVQEPPSIT IPMPPKTIRK QGDKGFSLTC RARGKPRPVV
SWYHNGEEIN LDNGLFRVET SETIEDANVY VLQTVLHFDS ITRRDNLLTA ADRGSYMCAF
DNGIGPIARA ESYLKIEHSP VLMHTHKRVA FDVGEVASLQ CKMSAYPEPK FEWLFKNKHL
DYFGNRYSTN VTEQPPNSDI YVATLTILET RPSDYGDYTC RAMNSIADYH QTNIKLVEKS
QPDSPTMLEV LEVLSDSVTL RWKEGFNGGF SNTEFIVTYY ADGERWRNES CRTMNPCKIT
GLESRTEYRF KVLAVNPRGY SSYSEEIREV TKVNLKDMPN AYDSHFESDK NILIFNVEQN
ALKLVAKIEA REGDNDQWSL LTTVPILNQR EKVLLRPPVS VYSDMRIILC LESNDSWCGY
SHLVKIDAVS SYLKESKVFS FEHLMLVICV GGSLAVVVVI FLVCCCYKKK ADVKKDYEAE
SDDNRPKVSA ISPPYYSGHD NKGLVNGNED PSKTSPPPMY TSNGSTNGHI PQNYYLTGDG
AEPSPNGSNE TAQSDVWMMK ADGMSDNALP YHPTYGSAHS PIDPNVYPYS YYPHEEYQPL
SEETYNMNMK NALCKLNALQ YKLIIHLFTD SPYYDDGHNA YGSTTGPPMM SDSISDQHML
SQDISKINHI SFDDETDYAG SRNGRPIREI IV
//
