ID A0A3S3PRN2_9ACAR Unreviewed; 856 AA.
AC A0A3S3PRN2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=PR domain zinc finger protein 1-like protein {ECO:0000313|EMBL:RWS17893.1};
GN ORFNames=B4U79_16036 {ECO:0000313|EMBL:RWS17893.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS17893.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS17893.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS17893.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS17893.1}.
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DR EMBL; NCKU01000021; RWS17893.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3PRN2; -.
DR STRING; 1965070.A0A3S3PRN2; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048869; P:cellular developmental process; IEA:InterPro.
DR CDD; cd19187; PR-SET_PRDM1; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR016608; PRDM1.
DR InterPro; IPR044413; PRDM1_PR-SET.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR16515:SF26; PR DOMAIN ZINC FINGER PROTEIN 1; 1.
DR Pfam; PF21549; PRDM2_PR; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR PIRSF; PIRSF013212; PRDM1; 2.
DR SMART; SM00317; SET; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 82..199
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 678..705
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 706..733
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 734..761
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 762..789
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 230..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 95504 MW; 7D78501327F6CBC4 CRC64;
MKQRAFGAVI DPNEVLAFDI EKNVIFGDRS PDLKLHRMED GAWDLNSIAE EDFEQLTVYI
VPDQPCDELG ENANRAEACL PRNLVLKPSQ TLSDVLGVWS TDYIPRGTRF GPLVGEIYRK
DEVPKDANRK YFWRVYTNGN DDYHYIDGYE VSKANWMRYV NPAYSSESQN LVACQVRQQI
YFYTIKPILP NQELLVWYCK EFAERLNYPL TGELMLQRIR QQLLPECKDY YTPNTRLTPT
DTTRSDEGYH SNGGQDDAFT PPEDSSDSDS DNNYVLDFSV KAKRSEKDRN KSPELDENKH
LNDKNEFRRV KIKMPKAYTY RSTLSPANKA RKDELDESCK PTSLAPDSGE RGYSDTEPSS
PKPSPHPDES GGNTSGQNLK RVTNGSSVSP NSNLPLSGYE GMCQRISNGS PKSPNNSPST
GILENLLLQR FHAERQPSPN GKSNSVKDPV HVIINGDNKR NEATNGNSHQ SVISSLHSGA
NRSPNSENGH IIYPHKKNYR AVSSSGHSPE MHSPDSTDKT HVNGSGLMGS SGYPGSSYAG
FYLNGMPPMF SPAHFGMYAY STTAGLPPTD SVHNHHQTSP GHHLNSRVPN GSSPYNHSKL
PLPIDYPSPH LSVLQRSPTG LDPKSPFGRS SNGTPSPPSS IASNGVSSNG QLSPNSQQGR
GYRSLPYPLK KKDGKMHYEC NVCFKTFGQL SNLKVHLRTH SGERPFKCTI CSKSFTQLAH
LQKHHLVHTG EKPHQCDVCK KRFSSTSNLK THLRLHSGQK PYACDLCPAK FTQFVHLKLH
KRLHTNERPY TCQTCNKKYI SASGLRTHWK TTSCQPNAVS DFIDIDSSRP NSAFLSGPYS
DYSNGRGLSS PIHNTC
//
