ID A0A3S3Q4L7_9ACAR Unreviewed; 545 AA.
AC A0A3S3Q4L7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=B4U79_03431 {ECO:0000313|EMBL:RWS13044.1}, B4U79_13565
GN {ECO:0000313|EMBL:RWS13883.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS13883.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS13883.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS13883.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:RWS13883.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS13883.1};
RA Dong X.;
RT "Trombidioid mite genomics.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS13883.1}.
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DR EMBL; NCKU01001120; RWS13044.1; -; Genomic_DNA.
DR EMBL; NCKU01000856; RWS13883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3Q4L7; -.
DR STRING; 1965070.A0A3S3Q4L7; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd13243; PH_PLEKHG1_G2_G3; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR043324; PH_PLEKHG1_G2_G3.
DR PANTHER; PTHR45924; FI17866P1; 1.
DR PANTHER; PTHR45924:SF2; FI17866P1; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301}.
FT DOMAIN 1..179
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 407..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 62296 MW; 9FF080D118948B29 CRC64;
MITIDTKLDC FLFFKQGYLV YMSNASSSAS EDNKRSLTTE QILNLFGNIE DIYEFNSSFL
SELEKQDLEP VGIAKCFVKR AEGFDVYTQY CTNYPRTVSL ITDLMRIKET AEMFKERQLT
LKQSLPLGSY LLKPVQRILK YHLLLQNIVK NTDKESEGYE DIKNALSVMT NIACHINNMK
RKHEHAVRVQ EIQSLLYGWE GQDLTTYGEL MAEGAFRMFG AKAFRHLFLF EKMLLIAKKK
EGMLNYKTHI LCSNLMLIES IKGEPLCFHT IPFDNPRVQY TFQARNLDQK REWCLQLKRV
ILENYNAVIP SHAKQIVLEL GQSSQEENIH SSGKRTLSAP EYLERRKHDR NKSESLNHSL
HKGFKLRKSL KKLHAIDSIN GSRRIRSSSH DETAACALKD EALSGRRSSL GLMSSSDERS
DTNVTKEGRS DTKDLKEANV NILNVKVPPR TFRTGQSANA SETTEDYVTF YFNRNRVSPN
NACDDSGVCS PSSSDGSYNL RASTPISSDS GEFLIDENGL YLGLKSRNKN YCLSLFDKYT
DLIYE
//
