ID   A0A3S3Q885_9ACAR        Unreviewed;      1237 AA.
AC   A0A3S3Q885;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Cullin-associated NEDD8-dissociated protein 1-like protein {ECO:0000313|EMBL:RWS15710.1};
GN   ORFNames=B4U79_01178 {ECO:0000313|EMBL:RWS15710.1}, B4U79_02434
GN   {ECO:0000313|EMBL:RWS15707.1};
OS   Dinothrombium tinctorium.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC   Trombidioidea; Trombidiidae; Dinothrombium.
OX   NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS15710.1, ECO:0000313|Proteomes:UP000285301};
RN   [1] {ECO:0000313|EMBL:RWS15710.1, ECO:0000313|Proteomes:UP000285301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS15710.1};
RA   Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA   Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT   "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT   transferred genes associated with secondary metabolism.";
RL   Gigascience 0:0-0(2018).
RN   [2] {ECO:0000313|EMBL:RWS15710.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS15710.1};
RA   Dong X.;
RT   "Trombidioid mite genomics.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CAND family.
CC       {ECO:0000256|ARBA:ARBA00007657}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWS15710.1}.
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DR   EMBL; NCKU01000383; RWS15707.1; -; Genomic_DNA.
DR   EMBL; NCKU01000382; RWS15710.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3Q885; -.
DR   STRING; 1965070.A0A3S3Q885; -.
DR   Proteomes; UP000285301; Unassembled WGS sequence.
DR   GO; GO:0010265; P:SCF complex assembly; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039852; CAND1/CAND2.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR013932; TATA-bd_TIP120.
DR   PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12696; TIP120; 1.
DR   Pfam; PF08623; TIP120; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          49..85
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          1045..1208
FT                   /note="TATA-binding protein interacting (TIP20)"
FT                   /evidence="ECO:0000259|Pfam:PF08623"
FT   REGION          325..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..342
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1237 AA;  139291 MW;  BAE825EA6A7B58CD CRC64;
     MSTVSFQISN LLEKMTSSDK DFRFMATNDL MAELQKDSIK LDDDGEKKIV KMLLKLLEDK
     NGEVQNLAVK CLGPLVNKVK EHQVEIIVDT LCTNMVSEKE QLRDISSIGL KTVISELPQS
     STGLAANVSK KITGKLTSTI AMQQQKDVTV QLEALDILSD LLNRFGNLLV SFHPTIQEAL
     IPQLSSQRLA VRKRSITAIS YLVMSCNQTL FAKIIDILLE KLVENQKLKN SNVSVVRTYI
     QCVSAITRQA GHRFGKHLEK VVPLIAQFSE YEDDELKEYC IQAFESFVRR CPKEITPHVQ
     LIIQICLKYI CYDPNYNYDD ASVEEMEMDN SDSSESNEEY SDDDDMSWKV RRAAAKCLEA
     VIATRHDMVV EFYKTVSPVL IIRFKEREEN VKVDIFHAYN ALLKQTRPTH TDAEDAGNPI
     ALLESQVPNI VKALHKQLRE KSIKTRQGSF GVLNELINVL PGCLKEHSES LIPGILYSLG
     DKNSSSNMKI DALIFLNSLL KRHPPEIFHP HIQVLLPAVI SAVEDSFYKI SSEALLVLTQ
     MVRIIRPLET PSTFKYDGYL QIIYTCTFSK LKASDIDQEV KERAITCMGQ IISSFGDSMV
     AEVAVTLPVL VDRLRNEITR LTCVKALTKI AGSQFKLEIG ALRSFLAEAI PILASFLRKN
     QRTLKLSTLI LLDTLVKNYG EQFTVELISI ILQEVPPLIN ESDLHISQLT LSLLTSLTRS
     HQAFLSIIPQ KILPETLVLV RSPLLQGAAL QSVLDFLQAL VRSSFPGLDY MELVRQLTIP
     VSISNQNMGP SLHKQAYHSI AKCVAAITTL EKEQSLQTVR RYINDIKNPP SDVAHLFALL
     TIGEIGKNVD LTSITELKEL IIESFLSSSE EVKSAASFAL GSISVGNLKE YLPFVLQQIA
     TRDKRQYLLL HSLKEIISCQ SINPAMVQAL EPHLDSIWSL LFNHCECPEE GTRNVVAECL
     GKLTLMNPRL LLPRLQTYLK HPSPLARSTV VTAMKFTISD QPQAIDHLLR NCIGDFLRTL
     QDEDINVRRV ALVAFNSAAH NKPSLIRDLL DTILPQLYNE TKVRGELIRE VEMGPFKHTV
     DDGLDIRKAA FECMYTLLDS CLDRIDIFEF LNHVEDGLRD HYDVKMLTYL MLVRLSHLCP
     SAVLNRIERL VEPLKVTCSN KVKTTAVKQE FEKQDELKRS AMRALLALLG IPDADKNPKV
     MDFLNHIKTT PDLQVLFEQI QKDASSVNET SSPMETN
//