ID   A0A3S3RPB5_9ACAR        Unreviewed;       670 AA.
AC   A0A3S3RPB5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Equilibrative nucleoside transporter 4-like isoform X1 {ECO:0000313|EMBL:RWS02755.1};
GN   ORFNames=B4U79_05715 {ECO:0000313|EMBL:RWS02844.1}, B4U79_09875
GN   {ECO:0000313|EMBL:RWS02208.1}, B4U79_12491
GN   {ECO:0000313|EMBL:RWS02755.1};
OS   Dinothrombium tinctorium.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC   Trombidioidea; Trombidiidae; Dinothrombium.
OX   NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS02755.1, ECO:0000313|Proteomes:UP000285301};
RN   [1] {ECO:0000313|EMBL:RWS02755.1, ECO:0000313|Proteomes:UP000285301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS02755.1};
RA   Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA   Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT   "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT   transferred genes associated with secondary metabolism.";
RL   Gigascience 0:0-0(2018).
RN   [2] {ECO:0000313|EMBL:RWS02755.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS02755.1};
RA   Dong X.;
RT   "Trombidioid mite genomics.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC       {ECO:0000256|ARBA:ARBA00007965}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWS02755.1}.
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DR   EMBL; NCKU01008014; RWS02208.1; -; Genomic_DNA.
DR   EMBL; NCKU01007275; RWS02755.1; -; Genomic_DNA.
DR   EMBL; NCKU01007171; RWS02844.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3RPB5; -.
DR   Proteomes; UP000285301; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002259; Eqnu_transpt.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR   PANTHER; PTHR10332:SF89; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4; 1.
DR   Pfam; PF01733; Nucleoside_tran; 2.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        93..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        493..514
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        526..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        555..575
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        587..610
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        622..645
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          26..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  75617 MW;  7A7BC10DC9E237CF CRC64;
     MDENLSRGYV LLLNNKWKYS PRFHYKRRRK KQGNSSGKSG SKYQTNDNQC EEDEEYLQSS
     PSLQQSSMGN SSSSSGATAN FNFQTPPKDR CNLIYFGLLL AGVGFLLPYN SFVIAVDYFQ
     SRYPGTTVVF DMSFIYILVA FCAVVINNIL VEAISLFWRI NIGYFLSFLT LLIVALVEIG
     WESFQTDVSY KLNLLAVAIV SFGCTVQQSS FYGYTSMLPS RYTQAVMTGE SAAGLIVSFN
     RIVTKLLLDD EQVNTLLFFG ISITIVACCI IIHNLLQRTT FVKFYINICS ESTTTLTSVV
     ESDKRSGNKS NTYSSIFQDK CQQNEDLNLV VDISDGNNKD TNIEFGILSF TNPRESGIEF
     YSKSETVNNR LVTHSESTEF DMPFGIDDEE LQNYSPPVLP EPPRHGMRHS TTISSIASKS
     KSLMHTQRME RSDSLELVIN NSEDNQHSKE KKQKSRSKLC NSFAQKFKQN AYFSLYQRFR
     LGLIARWEVS KTIWPFMLAI STAYFVTLSL FPGIESEIIS CKLRSWMPVL LMAVFNVTDF
     LGKVIASFYY DLSAYQLMSF SCIRVLLIPL LTLCATPRMN PFFKNECWSI IFSAMLGLSN
     GIVGSLPMIL APTHVADDLK EMTGNIMTLS YSIGLTTGSA LAYLIDWALG EPIIFEEICI
     ENRLNNLTHV
//