ID   A0A3S3RVT6_9ACAR        Unreviewed;       942 AA.
AC   A0A3S3RVT6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
DE   Flags: Fragment;
GN   ORFNames=B4U79_03386 {ECO:0000313|EMBL:RWS08256.1}, B4U79_10249
GN   {ECO:0000313|EMBL:RWS08230.1}, B4U79_14698
GN   {ECO:0000313|EMBL:RWS06769.1}, B4U79_15223
GN   {ECO:0000313|EMBL:RWS06775.1};
OS   Dinothrombium tinctorium.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC   Trombidioidea; Trombidiidae; Dinothrombium.
OX   NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS06769.1, ECO:0000313|Proteomes:UP000285301};
RN   [1] {ECO:0000313|EMBL:RWS06769.1, ECO:0000313|Proteomes:UP000285301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS06769.1};
RA   Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA   Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT   "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT   transferred genes associated with secondary metabolism.";
RL   Gigascience 0:0-0(2018).
RN   [2] {ECO:0000313|EMBL:RWS06769.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UoL-WK {ECO:0000313|EMBL:RWS06769.1};
RA   Dong X.;
RT   "Trombidioid mite genomics.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWS06769.1}.
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DR   EMBL; NCKU01003886; RWS06769.1; -; Genomic_DNA.
DR   EMBL; NCKU01003884; RWS06775.1; -; Genomic_DNA.
DR   EMBL; NCKU01003072; RWS08230.1; -; Genomic_DNA.
DR   EMBL; NCKU01003062; RWS08256.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3S3RVT6; -.
DR   Proteomes; UP000285301; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR47508; SAM DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR47508:SF1; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 2.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000285301}.
FT   DOMAIN          200..326
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REGION          122..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        131..154
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RWS06769.1"
FT   NON_TER         942
FT                   /evidence="ECO:0000313|EMBL:RWS06769.1"
SQ   SEQUENCE   942 AA;  106700 MW;  3A5773C819438BE4 CRC64;
     WPTSLSQESF LLLDTVVSAQ STVQIQRFFE KPRFGIITTT GNKIGFVFIE ISATASNLRE
     KVTSEFKHVI KDQHYILIDK IGWPVAPHQE DKLLVFDLAR RGVIKIKLFE ADEINNKDES
     DGGFLRSAIS SESEDEMETE RTLEKTEETE SPQKIRRVSY DTEVTKALSD ITSERNEVSH
     QAIYSIPSSV STYSVSSSTN HKPILISYVR QEAERHARQL KTHLSDLGYE VFLDVDEIMG
     GHDWIDALNT AVVNCEVFVP LITPQYGLTI WTNREIKLAD IKNKLIIPVN FLDHWPPECL
     AIQFATTQFL NWKSREEIEE AYRTQGERAN DIKYWDEPFV HRAAQEIINI SKKVANSNGL
     GLSFDRSTFA STFVSSPHSQ IRNTFLQEDF VDKTDNISRE FTDNIDQESG TMEDLFETEK
     PIFKSSMALL QSVSITKKQS LIVISAHPKE RSFVEALRNK LHEYDYEVWS SLDMCIGMSF
     DHLNGNGEDI GSLTPTTPVF HSMPAFSSRE ESGIGNLASL MESEEIEAED TFIPPQTRRP
     RPRFLNTLIE DSTNNRRFSQ SSASDFSQNS LFTPEDLDKA KVFRQRVARA RVVITILSSA
     YCKSKTCKSQ AFYCDYRKTV VAALYEDCKI PHCLAKLVDQ DLIRRDIPAL MDPSNQNFLE
     SIASKVNSIV NASKESFKEK MTDAKIQSFG HYLTKNIPIR DKKKIVVFVT GGSKFYNTGS
     EAICSSIAQT LAAKENVVLV TSGFYGAAEA VGRSFAEQRT ALNKSLNLFH ILPKKEGSNL
     KLKCRQGQDK AFEKLPFGET LFVGDSLHER DAVIARIFNY CILIEGGPYS ARLAKEFIWN
     DNTVIPIMCT GGAASGLYDC SAKITEMPAC VDQSDWDMLK EKCATSEDIA SAVLRIIQSL
     VKWRNKNNSD RKYRFKNRRR YYGKNKNRNE STHEPKPGVV KV
//