ID A0A3S3SCJ4_9ACAR Unreviewed; 579 AA.
AC A0A3S3SCJ4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Metabotropic glutamate receptor 4-like protein {ECO:0000313|EMBL:RWS13506.1};
DE Flags: Fragment;
GN ORFNames=B4U79_07864 {ECO:0000313|EMBL:RWS13506.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS13506.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS13506.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS13506.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS13506.1}.
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DR EMBL; NCKU01000968; RWS13506.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3SCJ4; -.
DR STRING; 1965070.A0A3S3SCJ4; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15045; 7tmC_mGluRs; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF176; MANGETOUT, ISOFORM G; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:RWS13506.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 280..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 281..546
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RWS13506.1"
FT NON_TER 579
FT /evidence="ECO:0000313|EMBL:RWS13506.1"
SQ SEQUENCE 579 AA; 66189 MW; FB30FBA21993E542 CRC64;
SDGWSARNLV SDGNELEVEG TISIQPKANP VNGFDDYFLQ LTPKNNFRNP WFIEYWEAYF
KCKWPNSQAT PFNQFYKRNC NGNERMSYEN GYEPEKQLQF VSDAVLAFGY AFKAMHKELC
NGERGLCNQM LPIDGTLLLK YLKKVHFVGL SGDRFQFTKN GDGPVRYNLI HFKQIEPGVF
QWINVGTYEG ERLNLDLNKV QFHYSSDEIP VSVCSLPCNK GQAKKYIEGE NCCWHCFDCT
KYQILIGETR CSDCPNGFLP DEEKLNCIQI PEEYVKADSL IAIFAIGFSS IGILFTLYVI
YVFLRYIDTP VVRASGRELS FVLLIGLIMC FSLTFILLLK PSDIVCGIQQ LSIGISFALI
YSAILTQSNR IYRIFTSGKK TAKRPNFISP KSQLIICFTL VLIQLIFLLL WFAFSPPKAI
NLYLKREDNQ LICSSNVTDS YFIAFIYPIL LIIICTVYAI LTRKIPEAFN ESKHIGFTMY
TTCIIWLAFV PIYFTTKTNI TLNLTTMSIA INFSATVTLI CLFTPKIYII LLHPERNVRQ
SLMPFTKYGS LRKQCSSVPT NSTFKTELVV QSNGKRTIV
//
