ID A0A3S3SMP6_9BACI Unreviewed; 789 AA.
AC A0A3S3SMP6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE SubName: Full=DNA translocase FtsK {ECO:0000313|EMBL:RVT67041.1};
GN ORFNames=EM808_00760 {ECO:0000313|EMBL:RVT67041.1};
OS Niallia taxi.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Niallia.
OX NCBI_TaxID=2499688 {ECO:0000313|EMBL:RVT67041.1, ECO:0000313|Proteomes:UP000288024};
RN [1] {ECO:0000313|EMBL:RVT67041.1, ECO:0000313|Proteomes:UP000288024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M5HDSG1-1 {ECO:0000313|EMBL:RVT67041.1,
RC ECO:0000313|Proteomes:UP000288024};
RA Tuo L.;
RT "Bacillus sp. M5HDSG1-1, whole genome shotgun sequence.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVT67041.1}.
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DR EMBL; RZTZ01000001; RVT67041.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S3SMP6; -.
DR Proteomes; UP000288024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000288024};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 453..649
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 219..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 470..477
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 789 AA; 87904 MW; 2F44A0CF1642BF2B CRC64;
MAKRKTRKTK KQQHLKKTIQ FELAALILIT LSFISILKLG AVGTTIVLFF RFFTGEWYIL
CLLGLIVYGG YLMWKREKPY LFHTKLNGIY LIVGAILLLS HVTLFNMLSS EGRFDNPSVI
FNTWELFWLE VNGKSTGMDL GGGMVGAVLF AMFHFLFDTA GTQIVSFLAI ITGVILLTGK
TLSGAFRKMM LSVWNFIKRQ WLAFIEDIRE WKESAAAKRE AKKADKQASR ARSQSQRRQR
TQEQEQLQEE EVQPLIVNPP IAHSEEPYAE PIISSFTANA YEDTQPQEEV SQAPAENDTE
EEAIVPITFT EVENKDYKLP PIKLLKAPKK ADQSGEYEQI HANAAKLERT FHSFGVKAKV
TEVHLGPAVT KYEVHPSEGV KVSKIVNLSD DLALALAAKD IRIEAPIPGK SAIGIEVPNS
EVAMVSLREV LETNKNDKPD SKLMIAFGRD ITGNAVCAEL NKMPHLLVAG ATGSGKSVCI
NGIITSILMR AKPHEVKMMM IDPKMVELNV YNGIPHLLAP VVTNAKKASQ ALQKVVSEME
RRYDLFSHTG TRNIEGYNDY VNRYNAEEDE KQPLLPYIVV IVDELADLMM VASNDVEDAI
TRLAQMARAA GIHLIIATQR PSVDVITGVI KANIPSRIAF AVSSQTDSRT ILDMGGAEKL
LGRGDMLFFP YGASKPVRVQ GAFLSDEEVE EVVDFVIGQQ KAQYQEEMIP DEITETTAKD
VEDDLYGEAV DLIVEMQTAS VSMLQRRFRI GYTRAARLID EMEARGIVGP YEGSKPRTVL
VPKVSEEIN
//
