ID A0A3S3SNG2_9ACAR Unreviewed; 1983 AA.
AC A0A3S3SNG2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Poly(ADP-ribose) polymerase pme-5-like protein {ECO:0000313|EMBL:RWS17753.1};
GN ORFNames=B4U79_02513 {ECO:0000313|EMBL:RWS17753.1}, B4U79_11888
GN {ECO:0000313|EMBL:RWS14015.1};
OS Dinothrombium tinctorium.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Acariformes; Trombidiformes; Prostigmata; Anystina; Parasitengona;
OC Trombidioidea; Trombidiidae; Dinothrombium.
OX NCBI_TaxID=1965070 {ECO:0000313|EMBL:RWS17753.1, ECO:0000313|Proteomes:UP000285301};
RN [1] {ECO:0000313|EMBL:RWS17753.1, ECO:0000313|Proteomes:UP000285301}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS17753.1};
RA Dong X., Chaisiri K., Xia D., Armstrong S.D., Fang Y., Donnelly M.J.,
RA Kadowaki T., McGarry J.W., Darby A.C., Makepeace B.L.;
RT "Genomes of trombidid mites reveal novel predicted allergens and laterally-
RT transferred genes associated with secondary metabolism.";
RL Gigascience 0:0-0(2018).
RN [2] {ECO:0000313|EMBL:RWS17753.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UoL-WK {ECO:0000313|EMBL:RWS17753.1};
RA Dong X.;
RT "Trombidioid mite genomics.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Target cell membrane {ECO:0000256|ARBA:ARBA00004175}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RWS17753.1}.
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DR EMBL; NCKU01000822; RWS14015.1; -; Genomic_DNA.
DR EMBL; NCKU01000040; RWS17753.1; -; Genomic_DNA.
DR STRING; 1965070.A0A3S3SNG2; -.
DR Proteomes; UP000285301; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0044231; C:host cell presynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0044218; C:other organism cell membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 7.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF12796; Ank_2; 7.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 26.
DR SUPFAM; SSF48403; Ankyrin repeat; 5.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 11.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Membrane {ECO:0000256|ARBA:ARBA00023298};
KW Neurotoxin {ECO:0000256|ARBA:ARBA00022699};
KW Presynaptic neurotoxin {ECO:0000256|ARBA:ARBA00023028};
KW Reference proteome {ECO:0000313|Proteomes:UP000285301};
KW Target cell membrane {ECO:0000256|ARBA:ARBA00022537};
KW Target membrane {ECO:0000256|ARBA:ARBA00023298};
KW Toxin {ECO:0000256|ARBA:ARBA00022656}.
FT REPEAT 860..886
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 901..933
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 937..969
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 970..1002
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1003..1035
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1339..1371
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1374..1406
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1408..1444
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1445..1483
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1561..1593
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1825..1857
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1983 AA; 221607 MW; D1161ABF79336705 CRC64;
MDLPKAETNG CSESGSLNHN SNVLQDTVTN LKNAVQQQIR GQMVFQNESS NADTVLTETV
TNMEPASKPQ SVPLSRVAEE KITKSTTGRC NKKNDVKAVK KPQQATKNQR RVTRRSPSTV
SLTNNHKTEA TVQLPVAHKS SPDVSINQMN CNSNSVAITK AGKSAQRTVS LKLTASPSNS
TSSLQNLSKR EEKNKGRRRK LATISKDAIK EEIDEPRVSK RVRLQYQPFQ SPESLAITPT
FYRSTPPSRN AEDKIIVFNK GDFLAVRNES GSFYICRTAQ NVYKSSKKFK IQWLNDEKDP
NIYTPDFYDV TDFECVLTNL RMIRLDKGKY RLPDEERQRI LNILQRALNV ERGVSEIPDP
RQVAMDGVDV SIVGKAEEEE LIKISPKIET KLENIKHKPV GRPKKKTSKE KVAENDTTQD
KVQTKVIKGQ RKNARNANRV SSNSSPLQNR RTTRSANASK SPSSSATVKS PLKSPAKSKR
VGIDSVVRKL RSKARISNQS KNVFDKVSVK TPRTVKEKKK KMSPNRKSPI GLSEIRRQKV
KAQLEPKPEV TLYERDPTFE APFADLPYIS SLAESRLLIK AVIVKDYDLL ERLMTEEKVC
SFCVKRCLAI KRDALSFAIE REDLKAIKLL TDQKYGDRFA SFPDIITIGD TATSPNSSVF
GFSSKSNLNR GRREITNALL KDIDTDYCTQ RQKINFSNDI IREALQFGVS IETLRKMISM
NPEKIDSTTI MILNNIVTAL RFGHRELAGE LVDMAIIKGG FGFNTLHKES LLKEGEPFSA
FKPSTVRKKS HLNSRITPIH CAALNPNPYY LSTLLQSQPD FSLQDNDGWQ PIHYSAVCRG
TGPLEYLISK SISTLQTDKE GNTPLHLACL TSAIHNVELI LSHEANSCND GSSCIEKQNK
AGLTPLHVAV EKGFADVVQI LLQSGADAEK TTAAMNDRLT PLMIAAQHGH LPILKMLVEK
GVDVETTDKK HRTALLHAVM NGHANAASYL LRLGANPDAK DNVGNTAVHY AAAYGWYFCY
KLLVEAGAKI NESNDGKVTP LLVAFLKGHM GLVELIAQKG IDINSHFEDA NGITLLMETV
MSKPGELFLS RLKFLIESQN VDCKKVDLEG NNALHYLVRS EANNNNYWKS YDEENCDEEA
ICGMEDVDVE KSHKNSLYEA ARMLIEHGCD PKAVNKHGES AFSLAAKHGC FTLMRKFLET
GCRINMTVNE DGNTILHLIV THILQDGASE FLRVLSKEPS AITVLKEMAK IYNVEGKTPL
LIALFRFRYL AKEEFSEKRK FIDFIRCLVD LLESDVDAFV QNEESDKDSC LHVAAKYCSS
EVLAILINKT SKIDVLNANQ KTPLTEALLN KNEEAAKFLI NSGSNINFKS VNDGDKSLLL
IAASSQKASL VPILLKKGAN VKEVDKESLN TALHFVVLSP HKKDAFHAVE ALIANGADVN
ARNKDGRTPL HLVVNARQGE TDASYEIEEF LIERGAKLDM KDNIGRVPLH YAFVKIDKED
DFSFIDPVEL VILTANGDEK VINSVDKFQH TPLHKAAFRG ATISCMQLIK NVSNMDALDN
NGNTALGLAV LYGHESCALM LLQNGANFTL SLNSSEKNSV ESDKSNIKIK CLMPNRKAKC
TILQEVIRRD WQGMLYLMLE QLEKMGKGIY SAIEAAIWAH RLKLVYKLIR KLKTNHRGSA
ERQTLFHILG QCVRSSDDKQ LQLDIVNMLL SKNINLNALD ESNSSAIIYS AINWNFVLCE
EFSRIIGFPM IAKQEPDIYL RTPFNAVFWN IGNEEIPTNM KDWCSNLLAH GADINSLCYY
PVAEENHSDI SYVNPAILCE NQMKRKYTPL IIAVIKKNYS AAKYLLQHKA DVNRCDDLDR
APLMHAVRMN DLKMVKLLLN PRYDPDKDPK PWNSRFLTFK QSSNAVLDAR DQNGWTITHH
LVAPFPNSEK TNSEVILRLL ARVGTPLNAA DKKGLTPFQI ASDCGLKHIV DTLQELTVVG
ESK
//
