ID A0A3S4RK74_MYCCI Unreviewed; 315 AA.
AC A0A3S4RK74;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=exopolyphosphatase {ECO:0000256|ARBA:ARBA00012451};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN Name=gppA {ECO:0000313|EMBL:VEG46090.1};
GN ORFNames=NCTC10485_00922 {ECO:0000313|EMBL:VEG46090.1};
OS Mycolicibacterium chitae (Mycobacterium chitae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1792 {ECO:0000313|EMBL:VEG46090.1, ECO:0000313|Proteomes:UP000282551};
RN [1] {ECO:0000313|EMBL:VEG46090.1, ECO:0000313|Proteomes:UP000282551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10485 {ECO:0000313|EMBL:VEG46090.1,
RC ECO:0000313|Proteomes:UP000282551};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; LR134355; VEG46090.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S4RK74; -.
DR Proteomes; UP000282551; Chromosome 1.
DR GO; GO:0008894; F:guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR003695; Ppx_GppA_N.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:VEG46090.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000282551}.
FT DOMAIN 20..311
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
SQ SEQUENCE 315 AA; 33411 MW; B8331B5043E95393 CRC64;
MANNPRLAAV DCGTNSIRLL ISEVRDGAVI DVHREMRIVR LGQGVDATGQ FDPEAIARTR
AALEDYATLM RSHDVSRVRM VATSATRDAA NREEFFAMTA EVLGAVVAGT VAEVISGTEE
AELSFLGAVD ELDAAAAPFV VVDLGGGSTE VVRGERHVDA SFSADIGCVR ITERCLHSDP
PTADEVAEAR TVIRERLDEA LAAVPVDNAR TWVGVAGTFT TIVALARRLT TYDSEAIHLS
QVSFGDLLPV CDELIGMTRK QRAALGPMHE GRVDVIGGGA IVVQELAREL GERAGIASLT
VSEHDILDGI IGSIV
//
