ID A0A3S4RX07_9ACTO Unreviewed; 484 AA.
AC A0A3S4RX07;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Sensory histidine kinase UhpB {ECO:0000313|EMBL:VEG28606.1};
GN ORFNames=NCTC11636_01626 {ECO:0000313|EMBL:VEG28606.1};
OS Actinomyces howellii.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=52771 {ECO:0000313|EMBL:VEG28606.1, ECO:0000313|Proteomes:UP000266895};
RN [1] {ECO:0000313|EMBL:VEG28606.1, ECO:0000313|Proteomes:UP000266895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC11636 {ECO:0000313|EMBL:VEG28606.1,
RC ECO:0000313|Proteomes:UP000266895};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LR134350; VEG28606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S4RX07; -.
DR KEGG; ahw:NCTC11636_01626; -.
DR OrthoDB; 3253720at2; -.
DR Proteomes; UP000266895; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:VEG28606.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266895};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..276
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 51564 MW; 0FE4F2C62E503EC5 CRC64;
MNTSVLSPAS SSEHSPTPSP GPSAVRADRS PGAPSHRWAH RTVTGQQPEL RSWPTHVPRW
LHGVYLVIGV VLIVLCPWGA VGEPGGLLFL LASLALSVSV PATSWSPVPG SLMALVAFAV
LAAAPQEATI VSTAVLLNAA TLHARGVPHA FAWAFTLSQL LVFTVANRGA SVVQDALLPW
GLLTAVAVLA GTAVRIVRGN ADHTRRRAAR ALTAQRQLMA RELHDTSVHD ITTMIMRAER
ARTHTTDPET LADLELIASV GHQAVGELRG LLHMMRLSDG ASAWSTALPA VLVPFDELIG
RAETELGQAG ISLTTHVEAD LEELPRQTRI NLARILGELF ANMGKYAVRG SSATVFIDLV
PGHLRCVAIN RVDPRALGGR HMRGSTSSQL GLVGIAERAS ALGGRSSFSE KDGVWMAQVT
LPTPSCRAAQ ATGRDPHPGR PARPHRRRHR PRPTSCSPTD NNTDRNDNDR VEPVDVVDSS
TSPA
//
