ID A0A3S4SCG2_MYCCI Unreviewed; 736 AA.
AC A0A3S4SCG2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Acyl-CoA dehydrogenase FadE6 {ECO:0000313|EMBL:VEG50027.1};
DE EC=1.3.8.1 {ECO:0000313|EMBL:VEG50027.1};
GN Name=fadE6 {ECO:0000313|EMBL:VEG50027.1};
GN ORFNames=NCTC10485_04343 {ECO:0000313|EMBL:VEG50027.1};
OS Mycolicibacterium chitae (Mycobacterium chitae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1792 {ECO:0000313|EMBL:VEG50027.1, ECO:0000313|Proteomes:UP000282551};
RN [1] {ECO:0000313|EMBL:VEG50027.1, ECO:0000313|Proteomes:UP000282551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10485 {ECO:0000313|EMBL:VEG50027.1,
RC ECO:0000313|Proteomes:UP000282551};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347}.
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DR EMBL; LR134355; VEG50027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S4SCG2; -.
DR OrthoDB; 3964153at2; -.
DR Proteomes; UP000282551; Chromosome 1.
DR GO; GO:0004085; F:butyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 2.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR43292; ACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR43292:SF4; ACYL-COA DEHYDROGENASE FADE34; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 2.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 2.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000313|EMBL:VEG50027.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000282551}.
FT DOMAIN 6..99
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 221..345
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 383..474
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 478..568
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 584..730
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
SQ SEQUENCE 736 AA; 78136 MW; B84AAB14C1D94C17 CRC64;
MPIAISPEHV DLADSVRALV ARVAPAEVLH EALETPIPNP PPYWKAAAEQ GLQGLHLAES
VGGQGFGILE LSVVLAEFGY GAVPGPFVPS AIASALIAAH DPNAQVLSGL AAGETIAAYA
IDSGLTATRQ GDALVIRGEV RAVPAAAQAS VLVLPVAGLD SATSGAEWVV LDADTLEIEP
VQSVDPLRPV AHVRANAVEV GDDRVLSNLS RSAAHALMST LLSAEAVGVA RWATDTASAY
AKIREQFGRP IGQFQAVKHK CANMIAVTER ATAAAWDAAR AIDEVARGDS DLEGAHIDFA
AAVAATLAPA AAQRCAEDCI QVHGGIGFTW EHDTNVYYRR ALVIAASFGR AADYPQRVVD
AATATGMRGI DIDLDPDTEK LREEIRAEVA ALKAIAREER NTAIAEAGWV QPHLPKPWGR
AATPIEQIII AQEFATGRVK RPQMGIAAWI IPSIVAFGTD EQKQRFLPPT FRGEMIWCQL
FSEPGAGSDL ASLSTKATKV DGGWRITGQK IWTTGAQFSQ WGALLARTNP SAPKHNGITY
FLLDMASEGV EVKPLRELTG NAMFNTVFID DVFVPDDMVL GEVDRGWEVS RNTLTAERVS
IGSSEPPFLP SLDKFVEFVG EGHFDQIEQN RAGQLIAEGH AAKLLNMRST LLTLAGGDAM
PSAAISKLLS MKTGQGYAEF AVSSFGTDGV LGDEQTPQGI WAQFLLASRA TTIYGGTSEV
QLNIIAERLL GLPRDP
//
