ID A0A3S5ESR5_9ACTN Unreviewed; 455 AA.
AC A0A3S5ESR5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Proline porter II {ECO:0000313|EMBL:VEH70612.1};
GN Name=proP {ECO:0000313|EMBL:VEH70612.1};
GN ORFNames=NCTC12967_01914 {ECO:0000313|EMBL:VEH70612.1};
OS Arachnia propionica.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Arachnia.
OX NCBI_TaxID=1750 {ECO:0000313|EMBL:VEH70612.1, ECO:0000313|Proteomes:UP000273044};
RN [1] {ECO:0000313|EMBL:VEH70612.1, ECO:0000313|Proteomes:UP000273044}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12967 {ECO:0000313|EMBL:VEH70612.1,
RC ECO:0000313|Proteomes:UP000273044};
RG Pathogen Informatics;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LR134406; VEH70612.1; -; Genomic_DNA.
DR RefSeq; WP_061786804.1; NZ_LR134406.1.
DR AlphaFoldDB; A0A3S5ESR5; -.
DR GeneID; 64407367; -.
DR Proteomes; UP000273044; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43045; SHIKIMATE TRANSPORTER; 1.
DR PANTHER; PTHR43045:SF1; SHIKIMATE TRANSPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000273044};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 24..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..432
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 455 AA; 49263 MW; 4BA7C21F0F210343 CRC64;
MATSTAAPDE LADAPKRQPK KSAIAALVGS ALEYYDFFIY ASASALVFNR LFFDPSNPAV
ATLLSLATFG VAYVARPVGA FVLGRWGDLK GRRVVMVFTL FLMGIATFAI GCLPTYDQIG
VTAPVLLVTC RLAQGFSAGG EQSSANSMSL EHAPDNRRSF TTGWTMFGTQ LGQVIAAGVF
IPMAAIGEEF FMSVGWRIPF WLSALVVLVG WLIRRTLEEP PQFQAQAAEA GPRVKRDPMR
ILITRYWGPL VAVTILALHN FETTIFSVWA LSYGKAQGIA EAHMLSQTVL VQLSALAAIP
LWTLLADKLG RKKIYIGGYI VVAVLLWFYM TQLHDANVIG VYLLGFVMQG IFYSAVNGVW
PAFYGEQFPT KVRLSGTSLG TQIGFTITGF APTIAAALVI GDATDFTPVY LLTIAVMAAV
LLTAAFGTRE TAFKSLDQLD EEADEAEVTK YGHSL
//
