ID A0A3S5ISK9_TRYRA Unreviewed; 1065 AA.
AC A0A3S5ISK9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative calcium-transporting ATPase {ECO:0000313|EMBL:RNF11920.1};
DE EC=3.6.3.8 {ECO:0000313|EMBL:RNF11920.1};
GN ORFNames=TraAM80_00615 {ECO:0000313|EMBL:RNF11920.1};
OS Trypanosoma rangeli.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=5698 {ECO:0000313|EMBL:RNF11920.1, ECO:0000313|Proteomes:UP000283634};
RN [1] {ECO:0000313|EMBL:RNF11920.1, ECO:0000313|Proteomes:UP000283634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM80 {ECO:0000313|EMBL:RNF11920.1,
RC ECO:0000313|Proteomes:UP000283634};
RX PubMed=30355302; DOI=10.1186/s12864-018-5112-0;
RA Bradwell K.R., Koparde V.N., Matveyev A.V., Serrano M.G., Alves J.M.,
RA Parikh H., Huang B., Lee V., Espinosa-Alvarez O., Ortiz P.A.,
RA Costa-Martins A.G., Teixeira M.M., Buck G.A.;
RT "Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to
RT Trypanosoma cruzi strains of high and low virulence.";
RL BMC Genomics 19:770-770(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNF11920.1}.
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DR EMBL; MKGL01000011; RNF11920.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S5ISK9; -.
DR VEuPathDB; TriTrypDB:TRSC58_00751; -.
DR OMA; CFTLYFA; -.
DR OrthoDB; 147844at2759; -.
DR Proteomes; UP000283634; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR24093:SF531; ATPASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF08282; Hydrolase_3; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RNF11920.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000283634};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 111..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 818..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 943..960
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 981..999
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1011..1034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 845..1033
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
SQ SEQUENCE 1065 AA; 116883 MW; 3AA87AA8E7C6F289 CRC64;
MQRGHTSVPI CSTNARECAA NALITALPDI IGHKRIGRFS SEIAGHQGLL NLLDVHCENL
MAWNNIHGIR GGILDTSVHE RRERFGANYL ARIPKKSFIS FVKESVEGDR ILQLLIGSAV
LSIVVGMITP EYREGNANLS TGWVEGAAIF LSVVIVVTLG ALNNYRKQEQ FAHIIESEDQ
TRQLVLVWRY ETASGGELLL RPMEIRSEDV VVGDVVQISA GMELTFDAIL FDNRHIVCDE
CSVTGENEEI VKDLHSDPFL ISGSSILDGS SDAVAVVCAV GERSFAGEIA MTIHGTEKRN
TPLQDQLEAL AERIGKFGLL AAILTFTALF LKEAYRIVVY GSPFSAMKFF ENLTTAIAIA
VVAVPEGLPL SVTISLAYSM RRMLQDGNLV RHLAACETMG GATVLCTDKT GTITLPEMKL
ARIFFQGHSY LREGNNLNGI IPGLDAIVTV SSPHSAAHLM ECVAANTLDP ELGRVRSRTG
EALMQLKSSI CIVAEDGHIT PFSYDEEPLL AVMRDKSSCV RFPFSSLQKK STTVLKLPNG
IYRVYVSGAP EMVLASCQSV VVENGRLAPL DDARRVYYES ILQDYAEAGL RTVCCAYGDI
NPLEEAVGLS GMPLTPPNIP LTFVVLIALE EAIRPEVPRS LELCARAGLR VIMITGDAML
TAINIAARCG LLDLARPSDF DTCHTSLSLG SPASLRAVET LIAEGYVMSG TDFRSLKDEE
FLDKFMLNIC VLARATPLDK KRVLRLLKLH NPLAVVAVTG DGTNDAPALK SSDVGFAMNT
GSDVAKRASD IVLLDNNFAG MVKATMWGRN VKGNIRKFLQ FQLTVNCVAC LIAFSGALMN
EQNMSPLKPV QLLWLNLIMD TLAALALATE LPSESALLSR PPESRNAPVI LPSMWFQVAT
QGGFQFVLQM HLLFSGNKHF KTRHVGEGLP DIFSSIEYFG PKHLSIVFNV FVIMQVMNFF
NARLLTQEET FFGRWGDSSG LLLIVSLIVV LQVCIVQYGG RLMSTVPLTA YEWMVCVMYA
MWSLVVGAIS RWWWWKVFRG KVRGTAHWTR WHLENLCNPS IAKRS
//
