ID A0A3S5ZPK1_BOVIN Unreviewed; 999 AA.
AC A0A3S5ZPK1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=RE1 silencing transcription factor B {ECO:0000313|Ensembl:ENSBTAP00000048755.3};
GN Name=RESTB {ECO:0000313|Ensembl:ENSBTAP00000048755.3,
GN ECO:0000313|VGNC:VGNC:96876};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000048755.3, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000048755.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000048755.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000048755.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000048755.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR PaxDb; 9913-ENSBTAP00000048755; -.
DR Ensembl; ENSBTAT00000039029.5; ENSBTAP00000048755.3; ENSBTAG00000011789.6.
DR Ensembl; ENSBTAT00000072386.1; ENSBTAP00000069498.1; ENSBTAG00000011789.6.
DR VEuPathDB; HostDB:ENSBTAG00000011789; -.
DR VGNC; VGNC:96876; RESTB.
DR GeneTree; ENSGT00940000155341; -.
DR OrthoDB; 4169790at2759; -.
DR TreeFam; TF332861; -.
DR Proteomes; UP000009136; Chromosome 6.
DR Bgee; ENSBTAG00000011789; Expressed in thymus and 111 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24403:SF102; RE1-SILENCING TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR24403; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 158..185
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 275..302
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 303..330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 331..359
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 360..387
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 962..984
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 81..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..630
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..690
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..731
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..864
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..923
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 110329 MW; 14A4231D5EC438DB CRC64;
MATQVMGQSS GGGGLFTGSG TMGMALPNDM YDLPDLSRAE LAAPQLIMLA NVALTGEVNG
GCCDYLVGEE RQMAELMPVG DSNFSDSDGE GLEESPEVKG EPSGLENMEL ESLELSVVQP
RPVFEVAAAS ETYSSNKDVP QETPVAEDKC KNLKTKPFRC KPCQYEAESE EQFVHHIRVH
SAKKFFVEES AEKQAKARES GSSTGEEGDF SKGPIRCDRC GYNTNRYDHY TAHLKHHTRA
GDNERVYKCI ICTYTTVSEY HWRKHLRNHF PRKVYTCGKC NYFSDRKNNY VQHVRTHTGE
RPYKCELCPY SSSQKTHLTR HMRTHSGEKP FKCDQCSYVA SNQHEVTRHA RQVHNGPKPL
NCPHCDYKTA DRSNFKKHVE LHVNPRQFNC PVCDYAASKK CNLQYHFKSK HPTCPNKTMD
VSKVKLKKTK KREADLPDNK LTSEKTETEQ TKGKGDVTGK KNERSVKAEK KDNVSKEKKP
CSNASSQVTT RTRKSAMEGK EVDVSPGNCS EKSCKSKKSK RKVEAEAHPL QEPVNDEEPV
TKKKRKAESK SKNSQEVPKG DSKVEENKKQ NICVKNSTKK KTVRSKSCKK SSQPAQRRPT
QMESAQVGCV QTEPLPHPSP PPPPPPPVGC GEVEVVQKGP VPMEPSPSME PVQVTPVEME
PSPLPPPPPE PAQVGSVQVE PPPPPPPMGD AEIEVVQKGP VETEPPPPME PIPRRSPRKD
NRKEKSSMLS EMARKEQVLI EVGLVPVKDK QLLKESASAQ DLFPPSPPLP KESLKGEESK
DQNLLPAGEG NEEAPLQKVE AEEAGKSLAG VAAVIKESAN TSSSEENLNM PEGETSEDKH
QAEAMLCEME MDTDEKKAEN FPSRDSAVEE PVSPPLSALP LEKHEAVSTT AVASPPVTVA
VNESQEMDED EGIHSHDGSD LSDNTSEDSD DSGLNGARPV PQETSGKDGK DALAVKVAAG
DFVCIFCDRS FRKEKDYSKH LNRHLVNVYF LEKAAQGQE
//
