ID A0A3S8WLU5_9ACTN Unreviewed; 314 AA.
AC A0A3S8WLU5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=EamA family transporter RarD {ECO:0000313|EMBL:AZM57829.1};
GN Name=rarD {ECO:0000313|EMBL:AZM57829.1};
GN ORFNames=DMA15_21635 {ECO:0000313|EMBL:AZM57829.1};
OS Streptomyces sp. WAC 01529.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2203205 {ECO:0000313|EMBL:AZM57829.1, ECO:0000313|Proteomes:UP000269043};
RN [1] {ECO:0000313|EMBL:AZM57829.1, ECO:0000313|Proteomes:UP000269043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC 01529 {ECO:0000313|EMBL:AZM57829.1,
RC ECO:0000313|Proteomes:UP000269043};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EamA transporter family.
CC {ECO:0000256|ARBA:ARBA00007362}.
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DR EMBL; CP029617; AZM57829.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S8WLU5; -.
DR OrthoDB; 369870at2; -.
DR Proteomes; UP000269043; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR004626; RarD.
DR NCBIfam; TIGR00688; rarD; 1.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF137; PROTEIN RARD; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..126
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 137..266
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT REGION 286..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 33422 MW; 95F1920FB9E69516 CRC64;
MWGLVPLFWP LLKPSGAAEI LAHRMAWSLV VVGVALLFVR RWGWARELVR RPRRLGLVAV
AAAVITLNWG VYIWSVNNGH VVEASLGYFI NPLVTIAIGV LLLGERLRPV QWAAVAVGLA
AVLVLAFGYG QPPWISLCLA FSFAVYGLVK KKVNLSGLES LAAETAVQFL PAVAFLVWLG
SRGDLTFGTE GAGHAALLAA TGVVTAAPLV CFGAAAIRVP LSTLGLLQYL APVFQFLLGI
LYFHEAMPPE RWAGFGLVWL ALSLLTWDAL RTARRNAARL TAARRAAEGA SSTSSAPSAR
SAPSVAPGER EPAA
//
