ID A0A3S8X0T8_9ACTN Unreviewed; 267 AA.
AC A0A3S8X0T8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Esterase {ECO:0000313|EMBL:AZM62749.1};
GN ORFNames=DLM49_27330 {ECO:0000313|EMBL:AZM62749.1};
OS Streptomyces sp. WAC 01438.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2203204 {ECO:0000313|EMBL:AZM62749.1, ECO:0000313|Proteomes:UP000271045};
RN [1] {ECO:0000313|EMBL:AZM62749.1, ECO:0000313|Proteomes:UP000271045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC 01438 {ECO:0000313|EMBL:AZM62749.1,
RC ECO:0000313|Proteomes:UP000271045};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP029601; AZM62749.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S8X0T8; -.
DR OrthoDB; 9786110at2; -.
DR Proteomes; UP000271045; Chromosome.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR012354; Esterase_lipase.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR11614:SF121; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF017388; Esterase_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000271045}.
FT DOMAIN 17..227
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT ACT_SITE 93
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 194
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 224
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT BINDING 25
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
FT BINDING 94
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
FT SITE 143
FT /note="Important for substrate specificity"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-3"
SQ SEQUENCE 267 AA; 28834 MW; D963317D2EF25C91 CRC64;
MPLLTGAEPY RHEGGQTAVL LCHGFTGSPQ SLRPWAEHFA AHGLTVSLPL LPGHGTRWQD
LGVTGWQDWY AEVDRELRLL RDRSSRVFVA GLSMGGALAL RLAARHGDAV SGVMVVNPAN
KVHGVAAHAL PVLRHLVPAT KGIASDIAMP RSREFGYDRV PLHAAHSLRN FFRLVDGELP
QVTQPLLLMR SPQDHVVPPA DSARILSRVS STDVTEILLE QSYHVATLDY DAERIFEEST
AFIGRLAPGA VKERGAGLGT EGTTTGG
//
