ID A0A3S9PJT2_STRLT Unreviewed; 708 AA.
AC A0A3S9PJT2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=EKH77_16705 {ECO:0000313|EMBL:AZQ72640.1};
OS Streptomyces luteoverticillatus (Streptoverticillium luteoverticillatus).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=66425 {ECO:0000313|EMBL:AZQ72640.1, ECO:0000313|Proteomes:UP000267900};
RN [1] {ECO:0000313|EMBL:AZQ72640.1, ECO:0000313|Proteomes:UP000267900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 15060 {ECO:0000313|EMBL:AZQ72640.1,
RC ECO:0000313|Proteomes:UP000267900};
RA Feng Z., Chen G., Zhang J., Zhu H., Yu X., Zhang W., Zhang X.;
RT "The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; CP034587; AZQ72640.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3S9PJT2; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000267900; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267900};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..331
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 540..674
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 708 AA; 74183 MW; 0EDDAA23675EB703 CRC64;
MLPSSKFGTR IAGLTCGRVT KWLVVLAWAA ILAVAFPLAG KLKSAETTDS TASLPSGAQS
TLVAEVADRF PGGDRITGIV VYSRDGGITA EDRAKADRDR QAFARLSGTD VAPARTSKDG
KALALGVSYP GDVEMEPLQK LQDQAKDGLP QGLDAHLTGS AGDRLDSLDS FKGLDGTLML
VAAGVVALLL LFTYRSPVLW MLPLIGAVVG SELANSVVYL LAKHAGLVVN GKLDSILVVL
VFGAGTDYAL LLIARYREEL RNHTDRHEAM AVALARGGPA IIASAGTVCF GLLCLMAAQL
KLNQSLGPVA AAGIVCVLIA MLTLLPALLT ILGRWVFWPL VPKPGTGART RRTIWDRIGS
GVSRRPRTVW IASTLLLAAL ATGAFGVKSG LDFEHTYRTT PDSVTGQKVL SEHFSGGGGN
PVRVVSEAGA ADEVAKALRG VKGVGEVKPA QLSKDGKLAA IPTVLTDAPT SQAAEDTVDR
IRDAIRDVPG ADAKVGNSAA ATLDIARAQA HDRKVVIPLA LAVVFVLLGL LLRALVAPLL
LIATVVVSYF SSLGASWLLF KHVLGFPAVD DTLIIYGFIF LVTLGVDYNI FLVHRMREEV
AGNPTDRGHR DGVLRSVSVT GGVITSAGAV LAATFAALAV LPLVSMTELG IMVALGVLLD
TFLVRSILVP ALALDTGRKF WAPSRLSARR TTPSAARPTD TLVGSGRR
//
