ID A0A401H3M6_9APHY Unreviewed; 1353 AA.
AC A0A401H3M6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 28-JUN-2023, entry version 15.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=SCP_1403970 {ECO:0000313|EMBL:GBE88989.1};
OS Sparassis crispa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Sparassidaceae; Sparassis.
OX NCBI_TaxID=139825 {ECO:0000313|EMBL:GBE88989.1, ECO:0000313|Proteomes:UP000287166};
RN [1] {ECO:0000313|EMBL:GBE88989.1, ECO:0000313|Proteomes:UP000287166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30375506; DOI=10.1038/s41598-018-34415-6;
RA Kiyama R., Furutani Y., Kawaguchi K., Nakanishi T.;
RT "Genome sequence of the cauliflower mushroom Sparassis crispa
RT (Hanabiratake) and its association with beneficial usage.";
RL Sci. Rep. 8:16053-16053(2018).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBE88989.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BFAD01000014; GBE88989.1; -; Genomic_DNA.
DR STRING; 139825.A0A401H3M6; -.
DR InParanoid; A0A401H3M6; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000287166; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000287166}.
FT DOMAIN 75..248
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1085..1245
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 136..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1286..1353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..512
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..550
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1290..1326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1353 AA; 153140 MW; DEE3FBD9641958F5 CRC64;
MDTFDLQEEL QAQQDLSNYE IRNEHDIPSM DPRGVAHVLE RAVEALAESS EAITDPAVFD
AYRSLLKHAE SLQGALMNKI LDSISSAFQA QVEGTLRDVE HEDQRTVAAH KAPLEMYAFL
LNWFVTAAEK VKASGEEDAA PAAPALKARR GRGGKAATTR TAAKKSAAEW TWVDQIPATL
ALISKVLRLK TQKIWLTTAE RDTFIQCITR PVYHITESEQ YMKVQPIRLG VYKVICLAVK
HHGHALAAQI SIMQSLQYYE HLSEPMAECL TVLAKEFDHA QLGDEILREI AGKSFNAQDS
KGPRAFSRFL IRLAELTPRS VLKQISLLLG HLDSESYPMR MAIVEVIGSL IRELALSSDL
TTDTHQVQKQ LNGLYELLLE RTLDLSSYVR TKVLAVLARL CDLPVKFPKQ RLAITRAAVD
SLEDKAASVR KGAVMLLVKL IVTHPYGLMH GGLLSLQEWE GRYKEATEKL DEVEGVVGKA
VERDEGEEEG EEEEDETEKA NDDEDEQSDD DDESPPKERS SKRRQKEKDR SDGMDVDEDE
EESQDVKMEE DNEEDNSRTP KPKPKSKKSK RSRKSELDMA ALTNEQVALA ALESNQLLHL
RLRKKYYAEG LNFIRQVEEG MENAERLLAS TNKLEVLEAI EFFRVTYEYQ FDGAQAGIQK
MLHLIWAKDN SATSEDGKEL KGVRSRLLEC YRSLYFDPLP DMEPKQQVNR IAKNMIELTY
DATLADLTSL EEMMRTMMDD SQIHSDVVAK LWQVYSSERL LPGPQRRGAA IILGMLALAK
RSVVADHVET LVKVGLGSKG KADLTLARYT CVALQRLNGS AKKVKGSLMD KSLRLDMENP
LFRKLQDAVE HPCRSKEWFG LAEQAINTVY ALGERPDIFC DSLIKDLTKR AFGQQNRAKT
PPLRDPDTME EDGAEVDPDN TGDHDQLEEE KDTGDAFALS QLLFVVGHVA IKHIVYLELV
EREWKRQKHE NEAAEKQAAG RRSSTRASKE REELDQVAGN VEDEIGERIA AIRETELLYG
SESLLSIYGP MLVHICGSPH KFKNRTLRAA ATLAFSKFLC VSSRFCDQHH QLLFKILETS
KDANIRSNIV IALGDVAVSF NSIIDENSNE LYKGLSDGDL IVKKNTLMVL THLILNGMIK
VKGQLGEMAK CLEDEDERIA DLAKLFFKDL STKENAIYNN LPDVISHLSV GAHAVEEPVF
QSTMRYIFSF IEKEKQAENI VEKLCQRFHL SEDPRQWRDI AFCLSLLPFK SERSVKKLIE
GLQFYRDKLH EEAVYSRFQE ILTKARSNKS SNKPDAELNE FEQILEDHKR QGEEDQEFEK
RVEGKKAAAK KRATRRTARK KAAQRDERHE ESE
//
