ID A0A401H5X0_9APHY Unreviewed; 798 AA.
AC A0A401H5X0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Uncharacterized glycosyl hydrolase {ECO:0000313|EMBL:GBE89814.1};
GN ORFNames=SCP_1701390 {ECO:0000313|EMBL:GBE89814.1};
OS Sparassis crispa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Sparassidaceae; Sparassis.
OX NCBI_TaxID=139825 {ECO:0000313|EMBL:GBE89814.1, ECO:0000313|Proteomes:UP000287166};
RN [1] {ECO:0000313|EMBL:GBE89814.1, ECO:0000313|Proteomes:UP000287166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30375506; DOI=10.1038/s41598-018-34415-6;
RA Kiyama R., Furutani Y., Kawaguchi K., Nakanishi T.;
RT "Genome sequence of the cauliflower mushroom Sparassis crispa
RT (Hanabiratake) and its association with beneficial usage.";
RL Sci. Rep. 8:16053-16053(2018).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBE89814.1}.
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DR EMBL; BFAD01000017; GBE89814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401H5X0; -.
DR STRING; 139825.A0A401H5X0; -.
DR InParanoid; A0A401H5X0; -.
DR OrthoDB; 69117at2759; -.
DR Proteomes; UP000287166; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF1; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:GBE89814.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287166};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 773..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..311
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 641..754
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 89563 MW; FAD7D6038F92DEA4 CRC64;
MISRSASEAS FILVGPEQAQ EQEKGASISS SLSTATVDTQ IPHPSPAAGL PAVSRSFAHD
WSRRGTGGKL SLHGRHFVDA HGRVCNLRGV NVSGSCKTPA NHDHDSFLAN HAEVTFVDRP
FPLEEAPEHF ARLRRWGLTL IRFLVTWEAI EHAGPGVYDL EYLEYLRSLL SLLPQFGITA
FVAMHQDVWS RYSGGSGAPA WTLEAVGFDL HGLEEPGAAW LKGVKGGGHV EEERGLWPCG
YQKLAAATMA TCFWAGDTFA PKLKVKHPQG EEVSIQTFLQ STFLDMWAIV VKTVGNLEGV
LGFEIMNEPH RGYIELQSMH EFDYNTDLHL GHVPTAIQSF MLGAGYPTEV GHWTRSWPFP
TRLTSQKVIN TSRQKAWRDD GPTEGRCLWE MHGVWGWDKS KNTSVVLRES YFKKHPMTGQ
KVEWYTDFYY PLINRWTDRV RSVSNAEKMV FLEPIPNEFC PSSWTVERRP SNMVYAPHWY
DLNALFSKAF GDFSVNVQGL SRGMFILRAL YWGQQGARDN FSLQIQNIVE EGYKSLGETP
VVIGECGLPM DMNKGEAFQT DNWFWQSRMM DAMITALERS LVGFTLWNYN PDNSDHTGDD
WNGENFSWFS RRRALSGAWL DLAQVSPTLD NGARILRSVV RPYPAKTAGV PLRFDYEINT
GQFTFEWANP QTSGKQDTAN SGGHASVRRP PLTDYPALTS KETEIFMPSI LAHSRKVVIA
GLHPQDSYHY DESRQTLTII ADDATPGVVH HVTVSLDPPL KAVFELNSFW SDFGAHVTAA
MVLIFAFIVY SVLSYLGY
//
