ID   A0A401IEH1_APHSA        Unreviewed;       839 AA.
AC   A0A401IEH1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:GBF79631.1};
GN   ORFNames=AsFPU1_1029 {ECO:0000313|EMBL:GBF79631.1};
OS   Aphanothece sacrum FPU1.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Aphanothece.
OX   NCBI_TaxID=1920663 {ECO:0000313|EMBL:GBF79631.1, ECO:0000313|Proteomes:UP000287247};
RN   [1] {ECO:0000313|Proteomes:UP000287247}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FPU1 {ECO:0000313|Proteomes:UP000287247};
RA   Kanesaki Y., Yoshikawa S., Ohki K.;
RT   "Physiological properties and genetic analysis related to exopolysaccharide
RT   production of fresh-water unicellular cyanobacterium Aphanothece sacrum,
RT   Suizenji Nori, that has been cultured as a food source in Japan.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBF79631.1}.
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DR   EMBL; BDQK01000003; GBF79631.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401IEH1; -.
DR   OrthoDB; 415644at2; -.
DR   Proteomes; UP000287247; Unassembled WGS sequence.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000287247}.
FT   DOMAIN          29..89
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          285..337
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          440..573
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          582..836
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   839 AA;  96048 MW;  C03AF8E8569D0BED CRC64;
     MSNVSEVRHI LVIADQKSRR IVPLAQSNYS IGRDPNSSIL LYDRQVSRHH ATLLRINDVQ
     NEQPCYRIVD GNLQGKRSTN GITINGKYCL SHELQPGDLV RFGSKSQANY YVIANSEELD
     LLKQGNNLGN KTSESNHLDT FLNDHTIMPL EELFIEDEEE NQETMRFGKV CQTNKPSHQI
     DLSSLIDSNP YPIIEINFPE KITYINPTAK VKFPDLNEVK LDHPILQGLV LNSSGKDETY
     LVREVKVDED YYEQHIYYAK DNNSLMTYLF DITKYKQREE KLRASKDRYR LFLEQGTEGI
     LLVDRQSKNI IEANQAYCKL LGYSSAEIIG LSLYELIALE REVIKQELVL VTAEKPYIIK
     ESLHRHRNGS LISVAGKISE TLYQGQEVFC LVIRDILERK QAEEKLKYQS LHDPLTNLPN
     RLLLNKQLAI ALAHAQRHQH LLAVIFLDID SFTHINNTLG HTIGDRVLQS FGKRLESCVR
     TGDTVSRWGS DEFTLLLPQI SNTEDTIKLA QRIFDNLQRP FIIEEHQLKI KCSIGIAVYP
     QDGENSEILL KNADAAMNRT KEQGRNHYQF YSPNLTDESS LLLRIESLLH QAIEKKQFYL
     HYQPQISLAT GKIVGMEALL RWQHPSLGVI PPQKFIPLAE KTDLMLHINK WVLKTACAQN
     RSWQKDGLPS IPIAVNLCSR EFQQPNLAEI VARVLDETAL DPQWLELEVT ELTLRQHLNL
     ARKTLKDLQN LGVRIALDDF GRGFSSLGYL KQFSFRTLKI DQEFIRDFRG TSEEMGLISA
     VLAIGRGFNI RVVAEGVETP EQLQLLREID CQEVQGYLFS YPLSAKEATE FLGKMAREP
//