ID   A0A401KDX8_ASPAW        Unreviewed;      1083 AA.
AC   A0A401KDX8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Helicase required for RNAi-mediated heterochromatin assembly 1 {ECO:0000313|EMBL:GCB17425.1};
GN   ORFNames=AAWM_00310 {ECO:0000313|EMBL:GCB17425.1};
OS   Aspergillus awamori (Black koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=105351 {ECO:0000313|EMBL:GCB17425.1, ECO:0000313|Proteomes:UP000286921};
RN   [1] {ECO:0000313|EMBL:GCB17425.1, ECO:0000313|Proteomes:UP000286921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 58123 {ECO:0000313|EMBL:GCB17425.1,
RC   ECO:0000313|Proteomes:UP000286921};
RA   Kusuya Y., Shimizu M., Takahashi H., Yaguchi T.;
RT   "Aspergillus awamori IFM 58123T.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCB17425.1}.
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DR   EMBL; BDHI01000001; GCB17425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401KDX8; -.
DR   STRING; 105351.A0A401KDX8; -.
DR   Proteomes; UP000286921; Unassembled WGS sequence.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd06008; NF-X1-zinc-finger; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:GCB17425.1};
KW   Helicase {ECO:0000313|EMBL:GCB17425.1};
KW   Hydrolase {ECO:0000313|EMBL:GCB17425.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:GCB17425.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286921}.
FT   DOMAIN          303..676
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          692..875
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1050..1069
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1083 AA;  122467 MW;  D51442EFB2363253 CRC64;
     MDSEEDHRPG TTGTTPKLSN KDVNAHMIVN KDIREYLVQP STDYAEEWLK RPEIPSAEEI
     LGNSGTGEDD YIELTPNKTE GPWKSSDEYL KAHYELLRED AVAPLRDAVA YVRDDPHMTD
     SKLVSIYDKV YFIGIKFAQR GLGIKIRFST SRAEKNIVWE YTKRLVSGSI IALSPADDVF
     QQKCVVAIVA ARPLEGVQKY PSEIDIFLAR PEDFEFDPQK EWIMVEAKDG YYESVRHTMA
     ALQKLKQERF PLSEHICLLD AHVGAPEYVE KNPIYDIQSV TEAAEGDKVD ILTNWPREPS
     QAMDSTQWQA LQEMLTKRLS LIQGPPGTGK TYVSVVALKV LLLNMKYGDS PIILASQTNH
     ALDQLLRLVA TFETSYIRLG SRSNDPEIKR RTLYCVRQNE PAVTVHGSVL GGARKEQKFL
     TQAIARILQP FNAENAHEPL PASLFVEYGL LTETQLDNLK KGAEGWTRPT DSEDTDPLVV
     WLGDKLVPFE VKYERESFGF EEDEVDLEYE QLKELEAEQG IEEDDYEILK GQFINLRDGL
     CGCKLACSEV SAIENLKQKD LWKVREEARG AVYDVLRKQL KTKMRETLLP QVSLYSKNCE
     NLHIGKWERD HHVLRTAKVI GMTATGLSKY RGLISSLRPK VVLIEEAAEA IEAPIVAACF
     DSLQHMILVG DHQQLRGHCT VQELGGEPYN LGVSMFERLV KNGMEYVMLN RQRRMAPEIR
     QLLEPIYGEL YDHESVRKRP GVKGMGTIRS YFFTHIWPES RDNLASKYNE TEAQMIAEFV
     VYLVQNGNTV KDITILTFYN GQRKKLLTVL RHHPYLQGQY VKVVTVDSYQ GEENEIVILS
     LVRSGENDIG FLSIANRVCV ALSRARRGFY MFGNANLLVK QNRLWRDVLT LMANNKPPRH
     LGAQLPVTCV EHKRTTFIQG LSDWNKINGG CDSPCDGVLD CGHPCPIKCH SFSHDQVECN
     EICNKRMACK HVCSEPCAIS HVCRCTCEMA SRLDDLRLHN ECQGSTGPLE GPSPYPEAVR
     HYQAFASGGA KEHDALLLKK ATETAAAAWP TPGIEEDEDL LPETSPQERD TTVLLSEENL
     MEI
//