ID   A0A401KX56_ASPAW        Unreviewed;       387 AA.
AC   A0A401KX56;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Sterol 24-C-methyltransferase {ECO:0000313|EMBL:GCB23717.1};
GN   ORFNames=AAWM_06602 {ECO:0000313|EMBL:GCB23717.1};
OS   Aspergillus awamori (Black koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=105351 {ECO:0000313|EMBL:GCB23717.1, ECO:0000313|Proteomes:UP000286921};
RN   [1] {ECO:0000313|EMBL:GCB23717.1, ECO:0000313|Proteomes:UP000286921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 58123 {ECO:0000313|EMBL:GCB23717.1,
RC   ECO:0000313|Proteomes:UP000286921};
RA   Kusuya Y., Shimizu M., Takahashi H., Yaguchi T.;
RT   "Aspergillus awamori IFM 58123T.";
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCB23717.1}.
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DR   EMBL; BDHI01000015; GCB23717.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401KX56; -.
DR   STRING; 105351.A0A401KX56; -.
DR   Proteomes; UP000286921; Unassembled WGS sequence.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR44068:SF4; S-ADENOSYL-METHIONINE-STEROL-C-METHYLTRANSFERAS (AFU_ORTHOLOGUE AFUA_4G09190); 1.
DR   PANTHER; PTHR44068; ZGC:194242; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:GCB23717.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286921};
KW   Transferase {ECO:0000313|EMBL:GCB23717.1}.
FT   DOMAIN          160..257
FT                   /note="Methyltransferase type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08241"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  43299 MW;  5614127430A0597F CRC64;
     MDTQTTVLAS RQSGRSSESS SLDAVEKQKL ANKELPQTRP DLHNSASPKR WKTFWKAFRY
     LNNLTPKQVD DFMASYVIYN LDWSDEKAMI ETLGPDYQAK VGDCLKAYYG VLNHLCALGD
     VEKMYIPPFM SKKATVLENQ LLYEESIAQD IGLSAGDHVL DLGCGRGRVA AHMTQYSGAK
     VTGLNIDPNQ IGQAKTYNEK LGFTNNSFVV QDFNSLPLPF EDASFDAFYQ IQALSLCKDL
     PSLFREIYRV VKPGAKISLL DWVSLPDYDP SNPEHAELMR RVKPLIGAVG TPTPESLEKA
     LTDAGFSVVR SDNASVGGLQ APLIDKVDFY FRSMRQVILG LVKTHVLPRH FKTLINRLCL
     DGEAFIKMDT MRLVTTSYRI IAQKPPQ
//