ID A0A401L8V8_ASPAW Unreviewed; 646 AA.
AC A0A401L8V8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Signal recognition particle receptor subunit alpha homolog {ECO:0000313|EMBL:GCB27910.1};
GN ORFNames=AAWM_10795 {ECO:0000313|EMBL:GCB27910.1};
OS Aspergillus awamori (Black koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=105351 {ECO:0000313|EMBL:GCB27910.1, ECO:0000313|Proteomes:UP000286921};
RN [1] {ECO:0000313|EMBL:GCB27910.1, ECO:0000313|Proteomes:UP000286921}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 58123 {ECO:0000313|EMBL:GCB27910.1,
RC ECO:0000313|Proteomes:UP000286921};
RA Kusuya Y., Shimizu M., Takahashi H., Yaguchi T.;
RT "Aspergillus awamori IFM 58123T.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}.
CC -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC {ECO:0000256|ARBA:ARBA00008531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB27910.1}.
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DR EMBL; BDHI01000029; GCB27910.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401L8V8; -.
DR STRING; 105351.A0A401L8V8; -.
DR Proteomes; UP000286921; Unassembled WGS sequence.
DR GO; GO:0005785; C:signal recognition particle receptor complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005047; F:signal recognition particle binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR CDD; cd14826; SR_alpha_SRX; 1.
DR CDD; cd17876; SRalpha_C; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.140; Signal recognition particle SRP54, nucleotide-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007222; Sig_recog_particle_rcpt_asu_N.
DR InterPro; IPR013822; Signal_recog_particl_SRP54_hlx.
DR InterPro; IPR036225; SRP/SRP_N.
DR InterPro; IPR000897; SRP54_GTPase_dom.
DR InterPro; IPR042101; SRP54_N_sf.
DR PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR PANTHER; PTHR43134:SF1; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF04086; SRP-alpha_N; 1.
DR Pfam; PF00448; SRP54; 1.
DR Pfam; PF02881; SRP54_N; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00962; SRP54; 1.
DR SMART; SM00963; SRP54_N; 1.
DR SUPFAM; SSF47364; Domain of the SRP/SRP receptor G-proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00300; SRP54; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:GCB27910.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000286921}.
FT DOMAIN 619..632
FT /note="SRP54-type proteins GTP-binding"
FT /evidence="ECO:0000259|PROSITE:PS00300"
FT REGION 148..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 70112 MW; 26AA13890BF3D9CB CRC64;
MLEAFEILTA SGVVLWSKSY APVGAHIVNS LINDVFIEEK VQLQATNNAA PSFKKEKYTL
KWKRVKEFDL IFVAVYQSLL QLGWIDKLLD NISTLYIDLY KDQLRSTRAR IAQYPFDKYF
DQQVRELEDK SGPISSEAFV AHAVDKKDPL VSSDNGGPPP PPVPGLLKAQ HQAALAGATS
DESTPPHTPD TSRSSTPVAN HIITAKGGPA GRVSRRARKA ANASANASSG DENRKGKTPK
SGKKMRKWDA DGFADEDDGQ ILDYSAHADG EEAAAPAVEG VSQDSWGHRT GKGQFVLKDL
GDEVHSILEN AESDKAKDVS SAGFVGSGFN AIGGLLRNIV GGKTLTEADL EKPLKTMEDH
LLRKNVAREA AVRLCEGVQR ELVGKKTGNF QSVDAALRSA MESSLRKILT PTSSLDLLRE
IDAVTSPTSK QQSPRPYVIS IVGVNGVGKS TNLGKICYFL LQNKYRVLIA ACDTFRSGAV
EQLRVHARNL RELSARENVG EVELYEKGYG KDAANVAKDA VEYGAANHFD VVLIDTAGRR
HNDQRLMSSL EKFAKFANPD KIFMVGEALV GTDSVMQARN FNQAFGTGRN LDGFIISKCD
TVGDMVGTLV SMVHATGIPI VFLGVGQHYG DLRGLSVPWA VNLLMK
//
