ID A0A401NGH9_SCYTO Unreviewed; 579 AA.
AC A0A401NGH9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Tripartite motif-containing protein 45 {ECO:0008006|Google:ProtNLM};
GN ORFNames=scyTo_0009095 {ECO:0000313|EMBL:GCB60019.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB60019.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB60019.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB60019.1}.
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DR EMBL; BFAA01003625; GCB60019.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401NGH9; -.
DR STRING; 75743.A0A401NGH9; -.
DR OMA; ERRCHIC; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19809; Bbox1_TRIM45_C-X; 1.
DR CDD; cd19785; Bbox2_TRIM45_C-X; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF291; TRIPARTITE MOTIF-CONTAINING PROTEIN 45; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00557; IG_FLMN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 34..96
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 128..174
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 185..222
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 393..496
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT COILED 284..315
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 579 AA; 64226 MW; 2EAD974E104BBAA4 CRC64;
MACVHYPKMS ESQEKTFAPC STSSERPRSC RTQCLICKNV YTDPKILPCL HTFCLDCVRG
LQQFSVPRTR GEGESGSGGS LDCTESAACI LCPLCDYEVH VPAAGLRGLT SNHLILNDIL
LESLKRSDCR IVCDLCNDGD AERRCHICST NLCDFCSKAH RRQKMTASHN TVALRDLQGG
NERLVQPIIC SAHPAEELRM FCETCDRLVC RDCCMVDHRG HNCDFIASVI SKHGIFIREL
LKQTQPHIGA LQETLQKIAH ARQLVQERLG MMTKEINNFT DGYIRALENH RNQLLKELEE
LRAQRENSLN LQQIQLEQIL ADMRTGVDFT EHLLTSGSHV EILLTKCVAV NRLKQLNKIG
YSTHPGEDDG MQFQPQERAG QCDGFEVFGI IVTKAVDPSK CVLQGEGLHV ARQDQSSEFV
LICNDQSGKQ MGRGGESIRV SIFNKKNKEC SLKTKLQDNH DGTYCFTYTP LVSGSYVGCV
CVKGQHVQGS PFTIAVTSKF RKHPGIFHCC TFCSSGGQKD VRCGCRGTMP GGYQGCGHGH
KGHPGQRHWS CCGKLTENSE CSGTLNGNTY QSLVRTVAL
//
