ID A0A401NKC3_SCYTO Unreviewed; 1006 AA.
AC A0A401NKC3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=UDENN domain-containing protein {ECO:0000259|PROSITE:PS50211};
GN ORFNames=scyTo_0014318 {ECO:0000313|EMBL:GCB61323.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB61323.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB61323.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB61323.1}.
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DR EMBL; BFAA01007635; GCB61323.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401NKC3; -.
DR STRING; 75743.A0A401NKC3; -.
DR OMA; PDSKDWI; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15288:SF6; DENN DOMAIN-CONTAINING PROTEIN 2C; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216}.
FT DOMAIN 623..966
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 1..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..307
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 112154 MW; F4DB58D6508DE155 CRC64;
MSDTRAGVLA TSDRPFSPST SRRVRDIVKE IEDALSQGSR NSTSKGPCTY KRPPTRNLDK
GQSAGASGEA LPPAGTIEHS SKVGPSRACI NDTQLLRHRA TGRGEAPRNG PGGVKKPLQK
MHSVGSAPSH GDRVGSRHHT VNIKQKISQW EGKTNTGTDQ HTPAEGALPP ECGCPLVAKT
ESPVGGNKKG LVKAKSLGLD FREGWNANDQ KVKSTHEKNG GEPNSRGLGS VIPQVKKLER
LVKNAPDSGK LLPPGNFYTS QNFWKKKMEG VLEDKNATCA SELKRKREST SSAEKDLDLR
NSENRETTIR NAENVYADSE ETDESRRINP VPKPRRTFKY AVDKNSKDAP PQGKLTSTKE
NVRSPPPLPA NPPPSAKALV TGTTLIKTNR KSFEFEDAEG LQILLTPATR ERNHNEGGNK
IKMTLCQTLS EENLYEDIIS PSKENPYEDV TFTPSFLSRG KRVWGSPSTR PRRPPKLPPK
PLSLLVQAQE SKTWNVSEPR KVNKDNTAPP LRSNPPSLPS NPEDPVGADA FVRKRKRIPA
LVLKIQAVYD IKRGKKKVKT LTLSGSDSTP LKDENSETES DTEEQQKAHN QRLVHVHSTL
KRNTRYQTLE RDLIELQEQK LFEYFVVVSL RKKALTNTYE PRVTQQFPSK LEKSTRQARD
AEEGLKMIPQ FCFPDVSEWV AVSQLTSETF SFVLTGEDGS RRFGYCRKLL ILDEVDKRRE
ISPALVYPFM RSVMEAPFPA PGRVITVKNF LPGSGNEVIE LCRPTDSRLE HVDFECLFGC
LNVRHVIHVF ASLLLERRVI FIADKLSTLS KCGHAAVAML YPFTWQHTYI PVLPAVMIDI
VCSPTPFLIG IHSNSVALLN DLPIEEVLVV DLCADRFLRQ VSAVLLPCLS SLSTLISEAC
VRFFVEIAGH YSLHMSVNEK GERFFQRDAF RKSHTSKNVR QFLELFMETQ MFAGFVQDRE
LRKSGVKGLF EVRAGEYLET IPETGSSGVN RFLKGLGNKM KFLSKK
//
