ID A0A401NX00_SCYTO Unreviewed; 2108 AA.
AC A0A401NX00;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=scyTo_0000417 {ECO:0000313|EMBL:GCB65403.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB65403.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB65403.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB65403.1}.
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DR EMBL; BFAA01000078; GCB65403.1; -; Genomic_DNA.
DR STRING; 75743.A0A401NX00; -.
DR OMA; CEKETTQ; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd21231; CH_DMD_rpt1; 1.
DR CDD; cd00176; SPEC; 6.
DR Gene3D; 1.20.58.60; -; 8.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF449; -; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00435; Spectrin; 9.
DR SMART; SM00033; CH; 2.
DR SMART; SM00150; SPEC; 14.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 11.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 27..131
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 146..252
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT COILED 1685..1712
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2108 AA; 243470 MW; A4335F18BF618E1D CRC64;
MAFLSHKLQS AAMFWCEEVE DDYEREDVQK KTFTKWINAQ FGKAGKPLIE DLFTDLCDGR
RLLELLEGFV GHNLAKEKGC TRVHSLNNVN RALQILQKNN VDLVNIGGSD IVDGNHKLTL
GLIWSIILHW QVKDVMKGIM ANLQQTNSEK ILLSWVRQSI YNYKPVNVIN FTSSWSDGLA
FNALIHSHRP DLFDWKDVAK LQSAHERLDH AFNVAKKYLG IEKLLDPEDI ATAHPDKKSI
IMYITSLFQV LPQQVTIEAI QEVETLPRQP KVTQEEQKEM LQKQHFSQQL SETLVQKPAG
SLLMEAEVDL DSYQTALEVV LTWLLSAEDS LQAQGSVSTD VEEVKEQFHA HEGFMMELTA
HQGSVGNILQ AGNQLIAEGK LSEDEENEIR EQMNLLNSRW ENLRVASMER QSKLHEVLMD
LQQQQLKHLA DWLTNTEDRI HQMEAQPLGP DLEALKQQVE EHKVLQEDLE QEQVRVNSLT
HMVVVVDESN GDNATAALEE ELQVLGERWA AICKWTEERW VLLQEILFKW QYFTEEQCLF
DEWLMEKEES VNKVQTTGFR DQNEMVANLR KLAILKGELE MKRQIMDKLC ALCQDLLMTL
KNKVVAQKLQ ARLEEFAQRW DDLVQKLENN SKQMSQSVTT TQTSLTQTML METVTMVTTK
EKISVAQKEE LPPPPPPKKR HVLLDSELRK RFDVDTTELH SWMTRSEAIL QSPEFAIYRK
EGSISDLQEK VNAIEKEKPE KYRKLQDASR SAQALVEQMV NEGISSADDI KQASEQLHNR
WEEFCQLLVE RMDWLQYQSK IITVSSQLQQ LEQAVISAES WLKAQQPPVT ESDTAKIQLE
KCKEEISRLT VLQPLVHKLT EQGAELQQKE EVPKSLGADI MASTSHFAHV LKALQTEEKQ
LHSLLQSLPT LRYKETMNTL VLWIQQCEAK LTVPRVTVTE YEIMEQRLKE LKVLQGSFQE
QQSGLNYLTT AAEEVSRKAP AEVSQKYRSE LEGIVGRWKK LSVHLMEQSQ KLEELMTKVQ
QFQNDTKTLK KWMAEVDVFL NEEWPALGDS EALEKQLEQC TALVNDIQTI QPSLNGINEV
GETLKSQAEP TYVGKLRTEL YELNACWENI CKQAYAKKTA LKGGLDKTMS LRKDLSEMQE
WIAQAEEEYL ERDFEYKTPE ELKKAVEELT RAKEEVSQKE VKVKLLSDGV NSFIEKAPPA
AHEALKSELD MLTGNYQRLC SRLNRKCKTL EEVWSCWCEL LSYLEAENIW LDELELKLRE
TENLQGGAEE ISEALDSLEN VMRHPEDNQN QIRELAQTLT DGEILDELIN ENLETFNSRW
EALIQQAVRR QKVLEQSIQS AQETDKTLRL IQESLALIDK QLTSYIADRI DAAQVPQEAQ
KVQSELTSHE ISLEEMKRRI QGPDAVGQSK SAGRVLSQIE ITQKKLQEVS TKFRLFQKPA
NFEQHLLECK RLLDEVKADL HILEMSSVEP EIVQSQLDHC MKLYKNLSEV KSDVETVIKT
GRQIVQKQQT ENPKELDERL TALKLQYNDL GAQVTEGKQE LEKSLKFSRK LRKEVNALTE
WLAATDAELT RRSAVEGMPT NLDSEVAWSK ATQKDIEKRR LLLNSITETG KSLKTMLGKS
DNVVDDKLSL LNCNWIAVTS RAEEWFNLLL EYQKQMENFD QNVAHITAWM YRAEILLDES
EKQKAGQKEE VLKRLKSELN DMRLKVDAVR DQALELMTNR GDHCREVVEP KLSELNQRFD
AISHRIKTGK QPVLEQVSVS PVTFLMDPDE LKNQKSFLAV QLKVQQQMFP KEMEQFDTHI
QKMLIELEAE IQQGENLKEG DFEKEMSEDD ERRMNELAKM GDTLQQSVTN EKKREEIRMK
QQMLQAKFNI LKDLRSIRRK KALEISPHWY QYKKQADNLM QWLDDIEKRL ASLPEPKDDQ
KIKEMDAELE EKRGDLNAVY RQAQSLSKRG AAKALELQLI QLNKRWSDIE SKFVQYRRLN
YPQIQSTYEE KIVTVLTEGI LPETSYVPSA YLAEIRQLHQ AVCDVEVLLK SLELQTKDFE
DFSQQDTCLK NIKRNLDELL GRVETVHSKK PGVLRSVSYT DGENIQDAVA QLDAKWENVN
KMWIDRQM
//
