ID A0A401P094_SCYTO Unreviewed; 672 AA.
AC A0A401P094;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Protein disulfide-isomerase {ECO:0008006|Google:ProtNLM};
GN ORFNames=scyTo_0004984 {ECO:0000313|EMBL:GCB66538.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB66538.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB66538.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the CRELD family.
CC {ECO:0000256|ARBA:ARBA00005897}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB66538.1}.
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DR EMBL; BFAA01001508; GCB66538.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401P094; -.
DR STRING; 75743.A0A401P094; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00064; FU; 2.
DR Gene3D; 3.40.50.11530; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR021852; DUF3456.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR039465; IL-17_rcpt-like.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR013568; SEFIR_dom.
DR PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR PANTHER; PTHR15583:SF12; INTERLEUKIN-17 RECEPTOR C; 1.
DR Pfam; PF11938; DUF3456; 2.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF08357; SEFIR; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00261; FU; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS51534; SEFIR; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..218
FT /note="SEFIR"
FT /evidence="ECO:0000259|PROSITE:PS51534"
FT DOMAIN 553..594
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
SQ SEQUENCE 672 AA; 74976 MW; AA0AE50B02001970 CRC64;
MVVGVTDDTL SDARKRWAPF LLLVLILFLI VIATITIKTQ LLKGCIKVIK WKPFATGSTV
ADSSSNRNVL LLYSLDHNQF EKLVNTFASV LCELQFQVIV DLWKRGEVGA QGPLPWVHSQ
KKKVADEGGK IVILLSKGAS MKYNEWLQST VSTEATYDPY DGFMASLNCV LPDIMKGHVS
GKYVVVYFED LQKKEEIPEV FSNMPIYSLP AQLSEFLQEL GVPANFKPEQ EATSHQSTIS
NRLHGVIKES LIFTMNICQL LSHRLFISPV LWFILYSIDP LLSLESTATK QDSCQICRRI
TENFRKGMEN TANKNFGGGN TDWENKNLAK YEISETRLLE IIEMVCESMN FDCNQMVEQN
EEHIENWWFK KQEEYPDLFQ WLCMDTIKVC CPPGTFGPDC SPCTGGSTKP CNGYGQCDGN
GTRSGTGLCN CDSGYAGSIC MECADGYFEE SRNETQLVCQ ECYKSCKKCT GPEDYKCQEC
KVGWFLHVDK CIDIDECDNE LANCKAGHYC VNMDGSYECR ACDKACLTCM GGGPSRCKKC
NKGYKMDGAK CLDIDECNSE KQVCNGAHEQ CKNTDGSYTC ACVDGFSKQD DLCVEDKLTP
VPEEGLFDNV TEDEMVVLQQ MFFGVIICAL ATLAAKGDMV FTSIFIGAIA ATAGYWLSEK
SDRLVDGFLK GK
//
