ID A0A401P7W9_SCYTO Unreviewed; 692 AA.
AC A0A401P7W9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=LON peptidase N-terminal domain and RING finger protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=scyTo_0008347 {ECO:0000313|EMBL:GCB69204.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB69204.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB69204.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB69204.1}.
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DR EMBL; BFAA01003171; GCB69204.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401P7W9; -.
DR STRING; 75743.A0A401P7W9; -.
DR OMA; CEICISE; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF4; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF13181; TPR_8; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 77..110
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 397..435
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 483..683
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
SQ SEQUENCE 692 AA; 77710 MW; B0070BBCFDC50BFC CRC64;
MSAVPSAAPE SGRAAGIKTR DCGQLEVASL QPEQLGGLVQ CLLYHFKRGH VAGTPDPEPG
HRVAAGGIGG GSGLLDCGGC REPLAQPVTL RCGHTWCRHC LRRNPRCPAC GEAAADLQSL
RPNVILSHLM AKWFPAEVRR TRDKIKLEEL VAQCRFPEAL TLLEQLELKP SDVALQSYRA
ESYAGLQLFK EAIEDMEAVC SRRPAWPEGY FRKARVLYTM GLVDEAVQSF LQCLALDEDF
TPAKVEVEKI LCGLLSPVLE NVKEGFLHRN KDLPAHLSTS AGCFHMAPNS TGFKDEISDV
PNSEGELACP SRTHSVQLLH KVENLVGLKR ISSAPLLSCQ DKTVLMKRKL AFSDQEIKET
GDGKSKHQKQ DTEQLFHSSS SERTIIKDLI DASDFECSLC MRLFLEPITT PCGHTFCKGC
LERSLDHNPL CPLCKDSLKE YLENRKYAVT YLLEEVIARY LSEELRERQS VHNEETAELS
NLTENVPIFV CTMAYPTVPC PLHVFEPRYR LMLRRCIETG TKQFGMCISD SHNGFTDYGC
MLHIRNIHFL PDGRSIVDTV GGSCFKVLQR GQKDGYYIAN IEYLKDIKVK GEELDKLVDL
HDEVYAQACR WFQNLKSRFH IQILQHFGPM PERESDLQGP PNGPAWCWWL LAVLPVDPKY
QLSVLSMTSL KSRLIKIQKI LTYFSSARDQ SK
//
