ID A0A401P8H6_SCYTO Unreviewed; 380 AA.
AC A0A401P8H6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN ORFNames=scyTo_0010548 {ECO:0000313|EMBL:GCB69393.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB69393.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB69393.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBUNIT: Interacts with PTBP2; the interaction is direct.
CC {ECO:0000256|ARBA:ARBA00034798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB69393.1}.
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DR EMBL; BFAA01004575; GCB69393.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401P8H6; -.
DR STRING; 75743.A0A401P8H6; -.
DR OMA; HMESVPP; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22436; KH-I_NOVA_rpt2; 1.
DR CDD; cd09031; KH-I_NOVA_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR047276; KH-I_NOVA_rpt2.
DR InterPro; IPR047274; KH-I_NOVA_rpt3.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF229; RNA-BINDING PROTEIN NOVA-1; 1.
DR Pfam; PF00013; KH_1; 2.
DR SMART; SM00322; KH; 2.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR PROSITE; PS50084; KH_TYPE_1; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 42..114
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 293..366
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
SQ SEQUENCE 380 AA; 38361 MW; 921EC664920A8916 CRC64;
MFYDLCTEDK IKVKCEKLVL ETLPSSPTTT KSSPSDPMTT TRANQVKIIV PNSTAGLIIG
KGGATVKAVM EQSGAWVQLS QKPDGINLQE RVVTVSGEPE QNRKAVELII QKIQEDPQSG
SCLNISYANV TGPVANSNPT GSPYANTAEV LPTAAAAAGL LGHANLAGVT AFPAVLSGFT
GNDLVAITSA LNTLASYGYN LNTLGLGLSQ AAATGALAAA AASANPAAAA AANLLATYAN
EASGGGSPVG GTVGTFALGS LAAATAATNG YFGAASPLAA SAILGSEKST DGSKDVVEIA
VPENLVGAIL GKGGKTLVEY QELTGARIQI SKKGEFVPGT RNRKVTITGT PAATQAAQYL
ITQRITYEQG VRAANPQKVG
//
