ID A0A401P9D0_SCYTO Unreviewed; 684 AA.
AC A0A401P9D0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Nucleolar protein 10 {ECO:0000256|ARBA:ARBA00015517};
GN ORFNames=scyTo_0012482 {ECO:0000313|EMBL:GCB69755.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB69755.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB69755.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB69755.1}.
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DR EMBL; BFAA01006039; GCB69755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401P9D0; -.
DR STRING; 75743.A0A401P9D0; -.
DR OMA; CNAIDVN; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 482..508
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 516..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 79863 MW; 6FFD997C959A59AF CRC64;
MQVSSVNDVK IYNLSYGRSL PEWLSDRKKR SLQKNDVDIR RRIELIQDFE MPTVSSTIKV
SRDGQYIIAT GTYKPRIRCY DTYQLSMKFE RCLDSEVVTF EILSDDYSKI VFLQCDRYVE
FHSQHGRYYR TRIPKFGRDF SYHYPSCDLY FVGASSEVYR LNLEQGRFLN SLQTDASQNN
VCDINPAHHL FATGTTEGKV ECWDPRTRNR VGTLDCALSS VTADTEIDGL PSISALKFKG
ALHMVVGTTT GQVLLYDLRS SRPLVVKDHH YGLPIKSIEF QEQLDLVISA DSRIVKMWNQ
NTGEIFTSIE TEHEINCLCL YPNSGMFFLA NESPKMNTFY VPTLGPAPRW CSFLDNLTEE
LEENPENTVY DDYKFVTKKD LENLGLAHLI GSPLLRAYMH GFFMDIRLYH KVKAMANPFA
YEEYRKDKIR QKIEETRAQR VQVKKLPKVN KELAMKFIEE EEAEEQVQRK KKGKSLPNIL
RDERFKVMFE NPDFQVDEAS EEFRLINPIV SKASEKRKKK LKQLQEHRDS EQEAEELEGK
PSDAESSESS DDDRGWVEEV QKQHKLLRRE QKLKLMERDQ QIHSKPKFFE IKAGEEFKSF
KDAARKQKLL KTTLEDRLKH EEKTGMLHLS DTTVGSKQLT FTLKKSEQQK KRQEAEKQHH
EERRRLRRSA GHLRGKAARG KPFF
//
