ID A0A401PFA5_SCYTO Unreviewed; 2217 AA.
AC A0A401PFA5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=scyTo_0001715 {ECO:0000313|EMBL:GCB71830.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB71830.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB71830.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB71830.1}.
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DR EMBL; BFAA01000396; GCB71830.1; -; Genomic_DNA.
DR STRING; 75743.A0A401PFA5; -.
DR OMA; WATHEAD; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF34; DYNEIN HEAVY CHAIN, CYTOPLASMIC; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000288216}.
FT DOMAIN 1515..1654
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1796..1937
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2217 AA; 253841 MW; 51A824DFCDEABEC5 CRC64;
MQNRYPEQPG DKRYPEPGHQ SKMFEIPDTS ACLPQHITKK RRKIGESLNP PILDIDPSEL
QARLISTAPK QINPNPRALK FSQNTKAREK RIAREQPIKL QPLPILKKYQ DKKQPEYIFA
KNRERLIKSG WKPPSVPTKR PRADSLDLTS QPVQQRLPKL TTDLPKKQID LDTCMLPPAR
QVKQRSIALC RTSSCMKMIL PPELTYSSTE DVIRENIEDP LKIISIIRKN KHLGFLYMNY
RAPKYSIKYD FYNLSVVAFE DINQNDYYTI SQDGVLHMNN EDIDFIELDR WEQEYLYHKQ
LIRIPVFALF RKWKAFTVWR KNVRSKKITN CRRALQDNLF IVNSSLRPAL LNISDMCHRI
GDMALCNIER GHTYTLEEFK TVQFQQLEEG AERLAQFRKI AQQTVKIACC TALLEAGFIP
DDYLFEMQSA GIGDVNVHST IATEILTESS DKINYTGQAN KRSHCRRLTC FIRLTDYLIV
NTLHVLTVNS ITLLVNHLME KLRQKPEEEL IRIWSTMDAE REAELEKKSV AQVVSIPAVE
DIQDEDLDDE DLENEGRQTE QVFVPMFLVD MILSYQDLLF RPPFGDFESG ISDFVLQMQG
IVLSVANLVS DSYFNAFTSP LINRKIEDKT CGEGPSLAAI LEDDMYLVET IQKILDSLES
GFHAAIIFAE MFEMFRVNFL ENESLDLDAI KKQEHDIFFF VSWLEKYHKQ HTDTVSIKQT
KNLGLLLIDN TALKKLLIPS PLRCLEAINE ILPVLAKMKT DAILHEVQDA EYKLEIIPTA
TMEYVNNLLF LDEMQDRIEV LEEESNIVVM MYQLVEKYKI GTPPEDLAVF ATLKPSINTV
RTVIDRAVSE RDSNVVKLCR CMDKDIDVLN EEVRAVRIKE QDPQLLDINT DREKVKTTLA
DMQTVMDELQ KRAFQYKSYQ KNFKVEISKF DLLEEVHADV KLKQLLWNSL NDWDVRVDEW
LQLKFETIDA EELTGEVAKY SKFVNQLEKG LPSNTVAATL KDNVEQMRQK LPVITDLRNP
FLKHRHWELI EHTVGAKLID VLEPVTLARL IELNAFDHAE EIQNLSGQAS GEAALETILK
KVEDGWKMTE FVVLPHREAK DIFILGGTDE IQALLDDSII NVSTIASSRY VGPIKHRVDE
WQRLLSLFNE TLEQWLTCQR NWLYLESIFC APDIQRQLPA EARMFTQVDK AWKEVMRKIN
RLPNALRAAT QPGLLEIFLN NNELLDQILK CLEAYLESKR VIFPRFYFLS NDELLEILAQ
TRNPQAVQPH LRKCFDAIAR LEFALASQTE EKTTEGEPEK VYTNDILAML SPEGEKVSLG
KGLKARGNVE DWLGKVEEAM FSSLRRLCKV SIADYQTQPR VQWVISGHPS QVILTIAQLM
WCRDLHHCLE GDHNRITVTA EFEKTNFERL NALAALVRGK LLSLHRSIVT ALITVDVHAR
DIVTELVIEK VDTVNNFEWQ RQLRYYWDLD ADNCVAMMAL SNYTYGYEYL GASPRLVITP
LTDRCYLCLM GALQLDLGGA PAGPAGTGKT ETTKDLAKAL AIQCVVFNCS EGLDYKMMGR
FFSGLAQSGA WCCFDEFNRI DIEVLSVIAQ QLITIRNAKA AKLTRFMFEG REIKLVMSCA
AFITMNPGYA GRTELPDNLK ALFRPIAMMV PNYALIAEVI LYSEGFESSK VLARKMTQMY
KLCSEQLSQQ DHYDFGMRAV KSVLVMAGSL KRENPDLNED VVLIRALRDS NLPKFLTDDA
LLFGGILSDL FPGVIIPDHD YGSFQQTTID VMLNRGLQAI PTMISKVIQL YETMIVRHGV
MLVGPTGSGK TTVYQILAET LGTLYNAGEK DPNYQIVKTY VLNPKSITMG ELYGEVNTVT
LEWNDGLMAI SVRAAVNDES KEHKWIVCDG PVDALWIENM NTVLDDNKML CLANSERIKL
TPYIHMVFEV QDLKVASPAT VSRCGMVYID ADELKWMPYV QTWMAGHADR LPYEPQQYLM
RLFTSCVENG LHYVNKKCTQ AISQVDISKV TTLCCLLESL LLAKDGPDLH MDPTQLNSVL
CQTFAFCYMW SIGGNLTENH WDGFDSFVRH QFEDHPEAKI PTSGDLWSYY MDFHNNRLDP
WDRIIPSFKY DSEIPFFEML VPTTDTVRFG YLLEKLLAVK HSVLFTGITG VGKSVVARSL
LNQIQDEASY VPLYINFSAQ TSSLRTQEII ESKLEKKRKN IIGRMQFHTC SKSVSVI
//
