ID A0A401PL41_SCYTO Unreviewed; 1076 AA.
AC A0A401PL41;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=P-type Ca(2+) transporter {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=scyTo_0002907 {ECO:0000313|EMBL:GCB73825.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB73825.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB73825.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB73825.1}.
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DR EMBL; BFAA01000756; GCB73825.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401PL41; -.
DR STRING; 75743.A0A401PL41; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:InterPro.
DR CDD; cd02081; P-type_ATPase_Ca_PMCA-like; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR InterPro; IPR022141; ATP_Ca_trans_C.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006408; P-type_ATPase_IIB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01517; ATPase-IIB_Ca; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24093:SF377; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF12424; ATP_Ca_trans_C; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 2.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 830..848
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 868..886
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 906..926
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 938..959
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 778..956
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
FT DOMAIN 1001..1034
FT /note="Plasma membrane calcium transporting P-type ATPase
FT C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12424"
FT REGION 160..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GCB73825.1"
SQ SEQUENCE 1076 AA; 117593 MW; 1EBBD28350DBDBA9 CRC64;
CGSAAGGVED EGESEAGWIE GAAILLSVIC VVFVTAFNDW SKEKQFRGLQ SRIEQEQKFA
VVRGGQVIQI PVSELVTGDI AQVKYGDLLP ADGILIQGND LKIDESSLTG ESDHVRKSAD
KDPMLLSGTH VMEGSGKMLV AAVGVNSQTG IIFTLLGAGS EEEEKKDKKE APQPPAHAVP
PQPLSTPGTE GAAGANATDS TNVSLVNGKM QDGNMENSQN KAKKQDGAAA MEMQPLKSAE
GGDGEEKEKK KGSTKKEKSV LQGKLTKLAV QIGKAGLVMS AITVIILVLY FAIDTFVIQK
LQWLPECTPV YIQFFVKFFI IGVTVLVVAV PEGLPLAVTI SLAYSVKKMM KDNNLVRHLD
ACETMGNATA ICSDKTGTLT TNRMTVVQTY VGDVHYKEVP DPDALPSKTL DVLVNAISLN
SAYTSKILPP EKEVGLPRQV GNKTECGLLG LVLDLKRDYQ TVREQTPEEK LYKVYTFNSE
RKSMSTVIKM QDGSFRMYSK GASEIVLKKC SNVLNAAGEA RVFRPRDRDE MAKKVIEPMA
CNGLRTICIA FRDFPGSPEP EWDNENVILM DLTCIAVVGI EDPVRPEVPD AIRKCQRAGI
TVRMVTGDNI NTARAIAIKC GIINPGEDFI CLEGKDFNRR IRNEKGEIEQ ERIDKIWPKL
RVLARSSPTD KHTLVKGIID SLHGERRQVV AVTGDGTNDG PALKKADVGF AMGIAGTDVA
KEASDIILTD DNFSSIVKAV MWGRNVYDSI SKFLQFQLTV NVVAVIVAFT GACITQDSPL
KAVQMLWVNL IMDTFASLAL ATEPPSEALL MRKPYGRNKP LISRTMMKNI LGHGIYQLTV
IFTLLFAGET IFNIDSGRNA PLHAPPSEHY TIIFNTFVLM QLFNEINARK IHGEKNVFDG
IFRNPIFCSI VFGTFAIQIL IIQFGGKPFS CIPLQIDQWL WCIVLGVGEL LWGQVISSIP
TNRLKFLKEA GHGTQKDDIP EEELNEDTEE IDHAERELRR GQILWFRGLN RIQTQIEVVN
TFKSGTSFQG ALRRQSSVTS QNQDVTNISS PTHVSLSTPN ALSSPTSASA ATAGQD
//
