ID A0A401PNR1_SCYTO Unreviewed; 946 AA.
AC A0A401PNR1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
DE Flags: Fragment;
GN ORFNames=scyTo_0003858 {ECO:0000313|EMBL:GCB74767.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB74767.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB74767.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC6 subfamily.
CC {ECO:0000256|ARBA:ARBA00006793}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB74767.1}.
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DR EMBL; BFAA01001085; GCB74767.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401PNR1; -.
DR STRING; 75743.A0A401PNR1; -.
DR OMA; FMCHRSL; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR19306; STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6; 1.
DR PANTHER; PTHR19306:SF6; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 63..290
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 243..372
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 946
FT /evidence="ECO:0000313|EMBL:GCB74767.1"
SQ SEQUENCE 946 AA; 109675 MW; 711B348317BE628A CRC64;
MSKRTKKLGD GTVPTKKVNT GSIEEFDIIE AGRRKENTGN CGQNGKNRPS LHWSASQVGI
IESISLKNFM CHACLGPITF GPHMNFVTGN NGSGKSAVLT ALIIGLGGKA TATNRGYAAK
EFVRNGENSA CISITLRNRG LDAFKPELYG EAIIVEQHIS SQGKRQYRLK SKSGHIISTK
KEELSMIVEQ FNIEVDNPVS VLNQEMSKLL LLAKSGEEKY KFFMKATHLE RMHEDYCQIM
QTKTITKEKI EKQDENVTQL KKKVKEKERQ YKNLASLNEL QEKLEHLKNQ MAWALVIEIE
KDLDSIKNCL QGEQRHSIKY NQKVEEWQAE VNSAELKVRA VQDQLQKMTE EKEQLVRELL
TLKEDIQRKK KACKESEVMF HCCKSQLKQL VKDHNYLQRR IEELNSGSLS SKANPTELKE
GINCLQGQLK ALKDQEVTIL QQIEDYYYAI SNFKDQQDNL RREEQSMKNV VQSRKRQLNE
LKASRMDRLK RFDGNMPALL YAMEEAHKQG HFQKKPVGPL GACFRLKYPE LALAVESCLK
GLLLSFCCDN YRDEKVLQTL MSRYFSSGRR PQINVCEFAN QEYNVKDSAV HHPDFPTVFD
SLEMSNPVVA NCLIDLRSIE RILLIKSNNR AREIMQQQKP PVNCREAFTA AGDQVFFNRY
YSSESDRARY LGGDVESEIS QLDVEVNEKM AQMLFYQQQL ESIEKGILIV HNHINNAQMQ
RKQIQQRITE IVIETADLES IEELQSVDIP TLKGEALYIW HRIESAQNKL EQARKEMNEH
WTLLDAAEHK YKEMKEKEYS LVEESDSVKR DIAKAKQICV QRLEVTRNPM SIDVEINCLR
ERINMTQERH GNKEEVTRQY FEVLEMQKNV QNQMKSLKKF MQLIDKIMEE RQKAYEKFRK
YISLRCKLYF ISLMSKQHYH GKINFDHKNM NLSITVQREE GVKTAR
//
