ID   A0A401PWR1_SCYTO        Unreviewed;       703 AA.
AC   A0A401PWR1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Zonadhesin {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=scyTo_0020009 {ECO:0000313|EMBL:GCB77594.1};
OS   Scyliorhinus torazame (Cloudy catshark).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB77594.1, ECO:0000313|Proteomes:UP000288216};
RN   [1] {ECO:0000313|EMBL:GCB77594.1, ECO:0000313|Proteomes:UP000288216}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA   Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA   Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA   Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA   Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT   "Shark genomes provide insights into elasmobranch evolution and the origin
RT   of vertebrates.";
RL   Nat. Ecol. Evol. 2:1761-1771(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCB77594.1}.
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DR   EMBL; BFAA01015546; GCB77594.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401PWR1; -.
DR   STRING; 75743.A0A401PWR1; -.
DR   OMA; HENCTER; -.
DR   Proteomes; UP000288216; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd06263; MAM; 1.
DR   CDD; cd19941; TIL; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000998; MAM_dom.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR025615; TILa_dom.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR   PANTHER; PTHR46160:SF4; VWFD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08742; C8; 1.
DR   Pfam; PF00629; MAM; 1.
DR   Pfam; PF01826; TIL; 1.
DR   Pfam; PF12714; TILa; 1.
DR   Pfam; PF00094; VWD; 2.
DR   PRINTS; PR00020; MAMDOMAIN.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00137; MAM; 1.
DR   SMART; SM00215; VWC_out; 1.
DR   SMART; SM00216; VWD; 2.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR   PROSITE; PS50060; MAM_2; 1.
DR   PROSITE; PS51233; VWFD; 2.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          3..160
FT                   /note="MAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50060"
FT   DOMAIN          185..363
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          570..703
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:GCB77594.1"
FT   NON_TER         703
FT                   /evidence="ECO:0000313|EMBL:GCB77594.1"
SQ   SEQUENCE   703 AA;  77208 MW;  15F833CD99ECA317 CRC64;
     CVLDCNFDVD LCNWTQSKTD NFDWKRISGS TPSSHTGPSY DHTTAGGYYI YLEGNEGSEG
     DRAHLVSAPC KTSGAQCLRF WYHMYGVAHS MALKVYQVEG GIPVLMWLET GNKGNRWIAG
     EVDLQLSGKS QILIEAVRGN DYRSDVAVDD ISFHTGCCGV TCDTIATTSF PTTASTVTSD
     TAGHAICSAS GDPPYNTFDT RVHHFMGTCT YVFSKPCSES SVLPYFDVST TNEHRGTNTK
     VSWVKSVHVF VYNNTLSIMK NHKVLLNGNR VNLPVSVKNL LVVRMSGAYV LLETDFGLMV
     RFDGIHHVDV SVPSTYAGLL CGMCGNYNGD PGDDIIMPNG SIATNSNKLG ESWQVPDGVI
     ECNHGESDFQ CDPNIKESAE KDTACGMITD LTGLFKECHA KVPPANYFGN CVYDLCTSGG
     QPTTLCFALQ TYADLCAQAG VCLQWRNNSF CPISCRSGSH YERCGTSCPA TCTDLSAPDS
     CLLPTVEGCF CDPGYVLSVD KCVPSSQCGC VDKNNKYFQM SENWFTHENC TERCTCLGKN
     IITCRTWQCG VLETCERRDG ELGCHMTGSA SCYVSGDAHY YTFDKIMYTF SGTCAYTLVK
     VCDNSSVVPV SITTLNEGHG QNLSTYLREI YIDVYGVHLT LQKNRRILLD GERIRMPIQG
     RLRGINVLTN GIYTIVETDF GMSVRYDGNH NLVIDLPNSY HSK
//