ID A0A401PXW4_SCYTO Unreviewed; 841 AA.
AC A0A401PXW4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=VWFD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=scyTo_0016770 {ECO:0000313|EMBL:GCB77984.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB77984.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB77984.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB77984.1}.
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DR EMBL; BFAA01010362; GCB77984.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401PXW4; -.
DR STRING; 75743.A0A401PXW4; -.
DR OMA; HITIENG; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR025615; TILa_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001846; VWF_type-D.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR46160:SF3; ALPHA-TECTORIN; 1.
DR PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR Pfam; PF08742; C8; 3.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF12714; TILa; 1.
DR Pfam; PF00094; VWD; 2.
DR SMART; SM00832; C8; 3.
DR SMART; SM00216; VWD; 2.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR PROSITE; PS51233; VWFD; 2.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216}.
FT DOMAIN 17..212
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 419..595
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 727..841
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 841 AA; 91905 MW; 411D7F8693509A47 CRC64;
MNGESSDEFQ LPNGTIVTSD VEFGKNWKVF DDDLLCADEC GNECRLCTQE QVTLYGGEGY
CGLMDKADGP FSTCRSALPP QDFIQSCTYD LCANEGSTLS LCQALNTYSA RCRVNGEAFN
LPVRLESGKI TLSQSGSAAL LQTDFGLRVS YDWNHYAVVS VPGIYSGSLC GLCGNFNGDG
VDDFLSPNGT TMSTASAFGN SWKTATSGAS CGGDPGLPSP LCTEADRRGY TSERSCGVLT
NTRGPFRQCH SVLSPTTYSE NCVFDLCVLA GKHETLCQAI ESYVAECQRR GVSIEDWRNA
TGCDVRCPEN SHFEVCGNPC HGNCVNVSVS SSCDLRCSEG CFCNNGYLRS GDSCVSPNQC
GCFHNGVYLK VGEAVLTDNC RSRCQCFARG DVRCVPAGCG RTEECTTRKG QRGCFSSFRS
CTVTGDPHYL TFDGALAHFQ GTGDYDIAKV SNPSSVPWFR VTVEKRHRRK NLVSFVSRVH
VYLLGVHITI ENGRGVLVNG TTVLTPHNIP SLATISHLDG FIVVDAVNNV EVHYDGRSTV
LVRVGPEYAN RLCGMCGDFN GNLMDDKVLP TGQRARSDNE FGNSWKTENS DLRCEDDNRN
VEVDGPRTAQ FQSLCSIILN QTGPFAVCHL HLDPMNYYTA CVYDLCVYGT NNLMLCGAIK
AYEKACNVQG VSIPSWQASQ NCPSQHPCEE QLCRGHEWCG EQRGVFGCFC EDGSGTTQDK
IYDYRLTCNG NNSEISLSRC LLFNDGWHSR YFHLNDPSCV GQVTNGRLVF HFDSSRRFCG
SNLKVNNTHF NHSNTIRASI IEGYGIVSRN RTISLEFSCA LPLTTNISFF ASDNVLQSGG
F
//
