ID A0A401Q4C1_SCYTO Unreviewed; 778 AA.
AC A0A401Q4C1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Metastasis-associated protein MTA1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=scyTo_0016136 {ECO:0000313|EMBL:GCB80220.1};
OS Scyliorhinus torazame (Cloudy catshark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=75743 {ECO:0000313|EMBL:GCB80220.1, ECO:0000313|Proteomes:UP000288216};
RN [1] {ECO:0000313|EMBL:GCB80220.1, ECO:0000313|Proteomes:UP000288216}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCB80220.1}.
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DR EMBL; BFAA01009550; GCB80220.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401Q4C1; -.
DR STRING; 75743.A0A401Q4C1; -.
DR OMA; HASQELD; -.
DR Proteomes; UP000288216; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd04709; BAH_MTA; 1.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF5; METASTASIS-ASSOCIATED PROTEIN MTA1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000288216};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 23..216
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 217..328
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 335..387
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 86..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 755..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GCB80220.1"
SQ SEQUENCE 778 AA; 88236 MW; 20F971390665D4DF CRC64;
AQACNYSYSV IVTSVAALSE YLWNRSVADY VYFENSSSNP FLIRRIEELN KTANGNVEAK
VVCFYRRRDI PSTLIGLADK HASQELDNCD PTLPTEVPDV PQETLPKTGA DSSWEETLGA
NTLSSCSSKD LEEEMETEAN LDNPQQLTEK QQHQLKHREL FLSRQLESLP ATHIRGKCSV
TLLNETEAVF SYLEKEDSFF YCLVYDPQQK TLLADKGEIR VGPRYQADIP DLLKEDEEDE
RDQIKLEVKI WDPDNPLTDR QIDQFLVLAR SVGTFARALD CSSSIRQPSL HMSAAAASRD
ITLFHSMDTL HKNNYDVSKA ISALVPQGGP VLCRDEMEEW SASEANLFEE ALEKYGKDFS
DIRQDFLPWK SLTSIIEYYY MWKTTDRYVQ QKRLKAAEAE SRLKQVYIPN YNKPNPNQIN
VNNAVSKPGM VNGAGFPGQN GGAGRACESC YTTQSYQWYS WGPPNMQCRL CAACWNYWKK
YGGLKMPTRM EGERPGPNRS SANPHGYWVK NANPKFTLKT RQAFCLQTTR LTKIARYFCQ
NLFHPRQAAR RPFIPINSAA IKAECTARLP EIGEKAIKLK PFVRKSLESI VKYLELHPSV
KPVSSLAVHS GSVTPARMPP VLNHGSPTIL GKRGYEQHNG IDGTMKKRLL MPFRGKTIAQ
SCSRLHPHPN HGQVRQMTAI NRGYMINGKP YSRNPKVLKP GSLPPMKGRR MNWIDAPDDV
LFIATDETRK VRKMLGPVDM KRAARQPYRQ ILIRQGRASS ASQQPRQPMN EEPIVIED
//
