ID   A0A401RTA6_CHIPU        Unreviewed;      1252 AA.
AC   A0A401RTA6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=VWFD domain-containing protein {ECO:0000259|PROSITE:PS51233};
GN   ORFNames=chiPu_0019855 {ECO:0000313|EMBL:GCC21385.1};
OS   Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC   Chiloscyllium.
OX   NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC21385.1, ECO:0000313|Proteomes:UP000287033};
RN   [1] {ECO:0000313|EMBL:GCC21385.1, ECO:0000313|Proteomes:UP000287033}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA   Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA   Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA   Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA   Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT   "Shark genomes provide insights into elasmobranch evolution and the origin
RT   of vertebrates.";
RL   Nat. Ecol. Evol. 2:1761-1771(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCC21385.1}.
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DR   EMBL; BEZZ01002195; GCC21385.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401RTA6; -.
DR   STRING; 137246.A0A401RTA6; -.
DR   OMA; LVCESPM; -.
DR   Proteomes; UP000287033; Unassembled WGS sequence.
DR   CDD; cd19941; TIL; 3.
DR   Gene3D; 2.10.25.10; Laminin; 3.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR   PANTHER; PTHR11339:SF371; MUCIN-5B; 1.
DR   Pfam; PF08742; C8; 3.
DR   Pfam; PF01826; TIL; 3.
DR   Pfam; PF00094; VWD; 3.
DR   SMART; SM00832; C8; 3.
DR   SMART; SM00215; VWC_out; 2.
DR   SMART; SM00216; VWD; 3.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 4.
DR   PROSITE; PS51233; VWFD; 3.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          15..184
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          369..544
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          837..1007
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
SQ   SEQUENCE   1252 AA;  138757 MW;  D12D31029F495EAA CRC64;
     MDDHCYGHNP NHNFRVCSTW GNYHFKTFDG DFYYFPGTCN YVFASQCLSS YEEFNIQMRR
     SIVNGFPRIS HIVLKVDGTV IEVQNSIISA DDNLVTLPYA HSGIVIEKVS NYTRITAKIG
     LTLIWNGGDA LTLELGQQFV NTTCGLCGDF NGIRDNEFYS NGYHLTPIQY GNLQKLNDPK
     EQCNDVPSSE QNKNCSTFES MCERALTDPG FSNCYDILDI APFIKSCMLD VCLCKDLEDP
     SSCMCNTLSE FSRQCAHVGG KPSNWRRKEM CEKTCQFNMT YEECGIPCAD TCSNPDRSRM
     CEDHCIDGCF CAPNTVLDDI SNTGCIPKEQ CPCTYNGLSY APGESYSTKC SKCNCNGGQW
     SCTDLSCPGI CSVEGGSHIN TFDEKQYTFH GNCHYVLAKD CENTFFTVLG ELQQCGITES
     ETCLKSVSLT DHRSQTIITI NPNGRVSVNG IFTELPLTFV NFTIFMPSTF HVIIHTSFGL
     QLQVQLVPIM QLYIRLDSVF KSRVCGLCGN FNNVLNDEFK IVSGLVEGTS AAFANTWKTK
     ASCPDRRDIH ENPCSLSVVN EKYAKYWCGL LLDDNSTFAQ CHSHVNPIQY FEQCKYDSCN
     CEKSEDCMCA ALSSYVQACA TKGIIISNWR MNVCFKYLTC PKTLIYSHSM TSCHRTCKSL
     GAPDKTCEID FEPVDGCGCA NGTYMEETGK CVPPSRCPCY YRGLTVPAGE VIHDEDAMCT
     CNQGKLECIG KELKFQACPA PMVYFDCNNA SADSVGTECQ KSCQTLDMEC YATGCVSGCV
     CPNGLVSDGS GGCIPINQCP CTHNGIQYHS GDIVQVDCNS CECKNRLWTC TDQQCHGTCM
     IYGDGNYVTF DGKRYNFNGD CEYIVAQDYC GNNTLDGTFR VVTENIPCGT TGTTCSKSIK
     IFLGNLEIKL SGGKYEVVKF GSGKHIPYEV RYLGIYLVIE AKNGLVLIWD KKTSLTIKLS
     HSFQSSICGL CGNYDGNVHN DFTTRNQLVV VNMEEFGNSW KVSPVCPNAK KNEDPCSVNL
     HRDAWAQKQC SILKDKPFLA CNSQINPTPY YEACVRDACA CDTGGDCECL CTAIAAYSLA
     CSMVGVCISW RNPALCPLFC DYYNPDDECE WHYAPCGIPC VKTCRNPGGA CSKIIPKLEG
     CYPDCPDDKP FLDEDKMQCV KLDHCPCYVN GNHYEPGHIV PSTHNCESCK CINSKVQCTY
     DKSGTFILHN VLSYIILSFN ASVFMMAKPS MKVILSTIQR MGLEGASKQY AA
//