ID A0A401RUR4_CHIPU Unreviewed; 2626 AA.
AC A0A401RUR4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=chiPu_0000277 {ECO:0000313|EMBL:GCC21895.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC21895.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC21895.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC21895.1}.
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DR EMBL; BEZZ01000003; GCC21895.1; -; Genomic_DNA.
DR STRING; 137246.A0A401RUR4; -.
DR OMA; RAVPCKV; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21309; CH_FLNB_rpt1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 24.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR PANTHER; PTHR38537:SF17; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 24.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 24.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 24.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 24.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 35..141
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 158..261
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 268..366
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 368..465
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 466..564
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 565..657
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 661..757
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 758..860
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 861..959
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 960..1055
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1056..1148
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1149..1243
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1244..1343
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1344..1436
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1437..1532
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1533..1628
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1629..1724
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1771..1840
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1840..1932
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1930..2018
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2021..2113
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2111..2209
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2212..2304
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2306..2399
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2403..2495
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2531..2625
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2626 AA; 279961 MW; 889731A2E3C26805 CRC64;
MSTHVQRREP EQLGDKDPEM PATEKDLAED APWKRIQQNT FTRWCNEHLK CVNKRIHNLQ
SDLADGLRLI ALLEVLSQKK MYRKYHQRPT FKQMQLENVS VALEFLEREN IKLVSIDSKA
IIDGNLKLIL GLIWTLILHY SISMPVWDDE GADDAKNQTP KQRLLGWIQN KLPDLPITNF
SNDWKDGKAL GALVDSCAPG LCPDWEIWDA AKPVDNAREA MQQADDWLGV PQVITPEEII
DQNADERSVM TYLSQFPKAK LKPGAPLKPK LNPKKARAYG PGIEPAGNVV MRPATFTVET
ISAGQGEVMV FVEDPENQRE EAKVTNNNDK NKTYTVVYVP KVAGRHKITV LFAGQHISKS
PFEVNIDKAQ GDASKVTARG PGLESTGNIA NKPTYFDIYT AGAGVGDVSI VIMDPQGSTN
TELTIEDKGN HTYRCTYRPV QAGHHTIQIA FSQSPIPKSP YSVTVGEACN PNACRATGRG
LQPKGLRIRE VADFKVHTKG AGSGDLKVMV KGPKGLEQPV KQRDLLDGGD AFSYEYYPVT
PGKHIVTITW GGHNIPRSPF EIQVGPEAGP QKIRAWGPGL DGGVVGKSAD FVVETIGTDV
GVLGFAVEGP SQAKIECDDK SDGSCDVRYW PTEPGEYAVH VLCDDEDIVD SPFMATIQPA
SSSFYPDQVK AYGPGLEKTG CVVHKPADFT VDAKDAGKAP LKIYAQDSEG IPISVQVKNK
GDGMTACSYT PTKPIKHTVA IAWGGVNVSN SPFRINIGQG SHPQKVKVFG PGVERTGLKA
NEPTHFTVDC TEAGEGDVSV GIKCDARVIS DSEEDIEFDI ITNPNDTFTV KYTPPAAGRY
TIKVLFAGQE IPVGSFRVKV DPSHDASKVK ADGPGLNKTG VELGKPTHFT VFTKGAGKAP
LNARFSGPTK GEAVCDFEII DNYDYSQTVK YTPTQQGNMG IAVTYGGDPI PKSPFNIDVA
YPLDMSKVMV NGLENRVEVG KDQQFTINTK GAGGQGNVDV KISSPSQKPV PCVVEPVTSK
DACVVKYIPK EEGLYSVDVM YDQNPIVGSP FTVDAALPPD PSKVKAYGPG LSSGLVGKSA
EFTIDTKGAG TGGLGLTVEG PCEAKIECSD NGDGTCSVSY LPNEAGEYLI NILFEDTHIP
GSPFKADVQL PFDPSKVVAS GPGLERGKVG EAALFTVDCS KAGPGELTIE PVSDKGVKAE
AHVQDNGDGT HTVSYIPLQH GPHTIAVKYG GQPVPKFPAR LQVDPAIDTS DIKVYGPGIE
GRGVFCDATT DFTVDANSLT KVGGNHIRAS IANPSGASTD CLIVDKGNGI YTVEYTPYEK
GVHTVDVTYD DAPIPNSPFK VGVIEGCDPS RVTASGPGLQ EGLTNKVNKF SVVTRGAGTG
GLGITVEGPS EAKISCKDNK DGSCSVEYTP YTPGEYDVNI TYGGQHITGS PFKVPVKDIV
DPSKVKCSGP GLSSGVRAKV PQCFTVDCSK AGKAPLQVAV LGPKGLVEPV EVIDNGDGIH
TVSYTPSLEG PYSVSVQYGD EDIPRSPFRV KVLPTHDASK VKASGPGLTS GVPASLPVEF
TIDAKDAGEG LLSVHVTDQE GKPKKANIHN NNDGTYKVSY IPDKTGRYTI VIKYGGDEIP
ASPYRIRAAA TGDASKCTMS GSGLGPTVQL GDELGMTVDA KAAGKGKVTC TICTPDGTEV
EADVIENDDG TYNIFYTAPE KGAYVVYVRF GGVDVANSPF SVVATDEVPI VPQQLVQQQS
LNAYPPGFQP WVLDGAYPPV DGLDGVGLKP FDIVIPFALR TGEITGEVRM PSNKTAKPEI
IDNKDGTVTV KYAPTEAGLH EMHIKYNGSH IPESPLQFFV NYGGSGHVSA YGPGLVYGVV
NKPATFTIVT EDAGEGGLDL AIEGPSKAEI SCVDNKDGTC TVSYLPTLTG DYSIIVKYNE
KHIPGSPFTA KVTDDSRRRS QVKVGSAADI SLDINESDLS LLSASIKSPS GQDEPCLLKR
LPNNHIGISF IPREVGEHLV SIKKNGKHVA NSPITIMVGQ SEIGDASKVK VSGPGLKAGR
TFEMSDFIVD TKDAGYGGLA LSIEGPSKVD INTEETEEGT CKVFYCPTEP GTYIVYIKFA
DAHVPGSPFT VKVTGEGRMR ESITRRRQAA SEATVGSICD LNLKIPEISV SDMSAEVTNP
SGQLDRAEIT ESDNHTYCVR FVPREMGVHT VSVKYQNKHV PGSPFQFTVG PLGEGGAVKV
RAGGPGLERG EVGVPAEFSI WTREAGAGGL SIAVEGPSRA EIAFEDRKDG SCGVSYVAQE
PGEYEVSIKF NDEYIPGSPY IVPIMASSED ASRLTVTSLQ ESGLKVNQPV SFAVRLNGAR
GLIDAKVHSP SGAVEDTHVS EIEPDKYAIR FIPHENGVHS IDVKFNGSHI TGSPFKVRVG
EPGQTGDTSL VSAYGLGLEK GTTGVQSEFI VKTANASPGS LSVAIDGPSK VKMDCRDCPE
GYKVLYTPMA PGDYQIGIKY GGPYHIQGSP FKAKVTGARL ISGGSTHESS SIIVESVTKS
TTVNSYSAVP KFASDSSKVV SSGAGLSMAN VGQKNCFSVD CSRAGSNVLL VGVHGPTIPC
EEVSVKHIGN EQYNVAYIVK ERGNYTLVVK WGDEHIPGSP FYITVP
//
