ID A0A401S2M7_CHIPU Unreviewed; 902 AA.
AC A0A401S2M7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=chiPu_0003077 {ECO:0000313|EMBL:GCC24675.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC24675.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC24675.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC24675.1}.
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DR EMBL; BEZZ01000064; GCC24675.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401S2M7; -.
DR STRING; 137246.A0A401S2M7; -.
DR OMA; KCQSVCH; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 6.
DR CDD; cd16697; RING-CH-C4HC3_NFXL1; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR000967; Znf_NFX1.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR12360:SF1; NF-X1-TYPE ZINC FINGER PROTEIN NFXL1; 1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR Pfam; PF01422; zf-NF-X1; 10.
DR SMART; SM00438; ZnF_NFX; 11.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 881..899
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 152..212
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 814..854
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 46..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 902 AA; 100470 MW; 7AB8017D35DD8A37 CRC64;
MEPAWRQGGR GRGRGRGKSG GGLPQAVGIV GEPEAGAAGD NRHGRGSSGS GWSSSSSSSD
WSRSQSEPSN ELSSLKKFEE IRKANQAAAQ RFANEDTSSE EEGEEDFEGQ QGKIVATTFT
AYSSHIGEDS SRELERTKQY LNDAFQSGAQ TCLICIASVK RNQAIWSCFR CYCIFHISCI
QKWAKDSIFL VSSVLDDDFG RKYHPWPCPK CRHPYEQSQT PTRYYCYCGK VEDPPPDPWL
VPHSCGQVCD KGFKPLCGHK CLLLCHPGPC PPCPKMVAIT CYCKKAKPVS RRCSAKGWSC
QQPCNQLLTC GQHKCENPCH TGNCPECPRV SRQRCLCGKE TAERLCARPQ WQCEKVCGRT
LSCGNHTCEQ VCHHGTCGNC PRSGYRACPC GKSKSALPCT EDIPTCGDTC DKPLACGLHR
CSMRCHRGPC ETCRQEVEKQ CRCGKHSKVL PCHKEYLCET KCIKLRDCQR HQCKRKCCSG
NCPPCDQNCG RTLGCRNHKC PSACHRGACY PCPETIEMKC NCGATVLVVP CGRERTTKPP
RCKELCRQPP TCHHVNREKH RCHFGSCPPC KQPCQKKLAK CTHLCPATCH DEVLVKQANS
RQPAGPWEQR SEPTFIRTAV PCPPCLTPIP MACLGKHEVS LLPCHAIGPY SCSRPCGRLL
ACLNHKCAKE CHVVAVIDED DKEKAGKECQ ICEEGCSKPR PSGCIHPCTL PCHDGACPPC
SQMIRMKCHC KITNLYVECT KMTTADAETK IVLNSCKNQC PKQLSCGHRC KAICHPGDCP
QSCNQKVKIK CPCKRIKKEI LCSVVTEEKV LVECDEVCQE MKQKASEMKE AEEKAALEKE
RLKQQVELEA FEKRLKGRRK KNKRRDTTET KETAWQKYRK YLMIPGCGIV LAMIAFYLLQ
LN
//
