ID A0A401S5E0_CHIPU Unreviewed; 907 AA.
AC A0A401S5E0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=chiPu_0004021 {ECO:0000313|EMBL:GCC25610.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC25610.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC25610.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC25610.1}.
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DR EMBL; BEZZ01000092; GCC25610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401S5E0; -.
DR OMA; GHQHTSH; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796:SF15; PATCHED DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 721..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 747..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..798
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 818..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..452
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 907 AA; 103536 MW; 330A6D1800438025 CRC64;
MSDELYRKSQ GWGFCKSCRR MLRQVVHSGL KGCFYWLGLF VSRHPVFFLT VPSILSILFG
ATFLNKFQRE TDLELLVAPK HSLAKIERTL VNSLFSINQS KNSLYSDLHT PGRYGRVVLS
SLPGADILER ADQILQMHKA VLEMRVNSSG FSYSFSHICM LRNSDKRCLF DDIIEVLEDL
SQAALSNNTA PRKSLRYPNT KLKDGRVTFI GHQLGGVIFI PNSREHQVKS ASAVQITYYL
QSYGSALQDV AEKWEAEFCQ LMLKFQQEHG DLQLYPLTSS GLWKDFYKTN TVARTEVVVS
LVLVLIAATL TSAMRDCLRS KPFLGLLGVI TICLSTVTAA GIFISTDGKY NSTLLGIPFF
AMGHGTKGVF ELLAGWRRTK EDQPFKERIA SAYSDVMVSY TMTSSLYIIT FGMGASPFTN
VESVKIFCQN MCVTILVNYF YIISFYGSCL VFAGQLEQNR YHSVFCCRIP SPEYLASRPV
WFKTMMNDGF QQSGSHDCDP YQKHFIQRFL REHYTEWIIN TYVKPFVVLL YLIYVSFSFM
GCLQISNGSN LINLLASDSQ SVSFTIIQQK YFSNYSPVIG FYIYEPIEYW NLTIQEDLQV
ISRGFIRISW IEHYLQYLKK LNITVLTKSE FINILANSFL KQPEFQNYVD DIIFSKTSDE
VDIIASRVYM VARTAENIHD EMVDLLETLR KHSLISRIKY IVFNPTFVFM DRYSSSITSP
ILNSSVSVLI ILMLTVLLVI NALGNVWVIL SVTSMEFGVV GLMTLWKVDM DSISILCLIY
SLNYAIDHCA PLLFTFVLEK ERTRTECIKN SLEWNGAAIL QSNICFLLGL MPLVFVPSNL
TLTLFKCLLL TATCTLLHCF VILPVFLTFF PPSKKRHKKK KRMERKEEIE CVEIRDNAGM
VDHVTTV
//
