ID A0A401S8Y7_CHIPU Unreviewed; 319 AA.
AC A0A401S8Y7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Peflin {ECO:0000256|ARBA:ARBA00041025};
DE AltName: Full=PEF protein with a long N-terminal hydrophobic domain {ECO:0000256|ARBA:ARBA00041490};
DE AltName: Full=Penta-EF hand domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042606};
GN ORFNames=chiPu_0005272 {ECO:0000313|EMBL:GCC26852.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC26852.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC26852.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00037873}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00037873}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC26852.1}.
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DR EMBL; BEZZ01000140; GCC26852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401S8Y7; -.
DR STRING; 137246.A0A401S8Y7; -.
DR OMA; HTRFQDS; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048306; F:calcium-dependent protein binding; IEA:UniProt.
DR CDD; cd16184; EFh_PEF_peflin; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR46212; PEFLIN; 1.
DR PANTHER; PTHR46212:SF3; PEFLIN; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 149..184
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 216..251
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 33938 MW; 3D7B7DC5B2AF22A8 CRC64;
MATYPYGSNY PGSSGPAPGA PPGSYFSSQH QAGGQYGPHS GQYGGPPPGS PYGGPQPSAP
YGTSAGGQYG NQAPGAPYGA PPPGGHFGAP AHGGQYGPSA PGAPYGSASS AGYYGGPAPG
GPYGGHPYGI PQQRQYGSGA SLAGDVPAGI DPEAFSWFQS VDADRSGYIS LNELKQALVN
SNWSTFNDDT CHMLLNMFDK SKMGKIDLYG FSALWGFLKQ WRNMFQQFDR DRSGTINTQE
LQQALTQMGY NLSPQFVQFL TTRFAQKPAR STIQLDSFIQ VCTQLQTTTD AFKEKDTNRS
GNVRINYEDF LTLAISRML
//
