ID A0A401S9W9_CHIPU Unreviewed; 928 AA.
AC A0A401S9W9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=Exocyst complex component 2 {ECO:0000256|ARBA:ARBA00017526, ECO:0000256|RuleBase:RU365069};
GN ORFNames=chiPu_0005622 {ECO:0000313|EMBL:GCC27198.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC27198.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC27198.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC exocytic vesicles with fusion sites on the plasma membrane.
CC {ECO:0000256|ARBA:ARBA00002660, ECO:0000256|RuleBase:RU365069}.
CC -!- SUBUNIT: Component of the exocyst complex.
CC {ECO:0000256|RuleBase:RU365069}.
CC -!- SIMILARITY: Belongs to the SEC5 family. {ECO:0000256|ARBA:ARBA00010578,
CC ECO:0000256|RuleBase:RU365069}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC27198.1}.
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DR EMBL; BEZZ01000155; GCC27198.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401S9W9; -.
DR STRING; 137246.A0A401S9W9; -.
DR OMA; RMWMDVD; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0000145; C:exocyst; IEA:UniProtKB-UniRule.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00603; IPT_PCSR; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR029175; EXOC2/Sec5.
DR InterPro; IPR039481; EXOC2/Sec5_N_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR13043:SF1; EXOCYST COMPLEX COMPONENT 2; 1.
DR PANTHER; PTHR13043; EXOCYST COMPLEX COMPONENT SEC5; 1.
DR Pfam; PF15469; Sec5; 1.
DR Pfam; PF01833; TIG; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483, ECO:0000256|RuleBase:RU365069};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365069};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365069}.
FT DOMAIN 8..91
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|Pfam:PF01833"
FT DOMAIN 133..918
FT /note="Exocyst complex component EXOC2/Sec5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15469"
SQ SEQUENCE 928 AA; 104810 MW; 4EAD252FAC66F822 CRC64;
MSRTRQPPLV TGISPNEGYP WTKVTIRGEN LGTGSMDLIG LTICGHNCLL TAEWISASKI
VCRVGPAKDD KGDIIVTTKS GGKGTSTVSF KLMKQEKIGI LEQSAVWVEE MNYYDMRTDR
NKGISPLSLR PANPLGIDID KGRILQKDLE GLFQGMSGDF TSEKFSATWY LIENHSATSF
DQLKVAANYL RKQANKKNEG SLAYVKGGLS TFFEAQDALS AIHQKLEVDG TEKVEGSMTQ
RLENVLNRAS NTADTLFQEV LGRKDKADST RNALNVLQRF KFLFNLPLNI ERNIQKGDYD
VVINDYEKAK SLFGKTEVRV FQKVYAEVET RIDSLRVRLM NKLLEMPSNL HDQKRYIRYL
SDLHAPGDPA WQCIMAQHKW ILQLMQNCRE KYIKGQKGST MLLGPMLDLD SDVRPSPISR
LTQAGSVKRA SSFQSSRDDS WRFKAPQPVT FVDNLTEIVI SQLPNFWKLW ISYVNGSLFS
ETGEKSGSVE KFKKNARSRQ NDFKKMIQEI INSLVKLIRG ALLPSSLAEV ELRQYGGWES
KMELSGQWLT HIIHTMRLNY ESLTALEIPN DLLQAIQELI LDLRVHCLII TLQQTADDVK
RLAEKEDWIV DNEGTTSLPA QFEHHVVQTL QSLKETIDCK PGETNIFQHE KNQQHVYELS
INIMKTFIDS LEYLSTKADG DLDSMHLSGL SVDMSSPDLL ASILENFSPT PEQKLLIVLS
NCEYLAHHTF KNLAQHFEMH AFHGTEKIAQ VSIDTVKNLD QHLFETYIEL KADPIVGSLE
PGIYAGYFDW KDCLVPTGVR TYLKEALVNI IAVHAEVFTI SKELVPRVLS RIIEAVTEEL
SRLMQCVSSF SRNGALQARL EICALKDAVA SFLTPESNYS FKQALEALPQ LSNGADKKLL
EELLNKFKSS MHLQLTCFRP STRSMVKT
//
