ID A0A401SEQ6_CHIPU Unreviewed; 580 AA.
AC A0A401SEQ6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Peripheral plasma membrane protein CASK {ECO:0008006|Google:ProtNLM};
GN ORFNames=chiPu_0007313 {ECO:0000313|EMBL:GCC28879.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC28879.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC28879.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC28879.1}.
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DR EMBL; BEZZ01000223; GCC28879.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401SEQ6; -.
DR STRING; 137246.A0A401SEQ6; -.
DR OMA; HKEQVNC; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd12035; SH3_MPP1-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR PANTHER; PTHR23122:SF40; PERIPHERAL PLASMA MEMBRANE PROTEIN CASK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..580
FT /note="Peripheral plasma membrane protein CASK"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019006711"
FT DOMAIN 56..109
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 144..225
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 266..336
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 393..565
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 228..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 66059 MW; 2148E3EA7E8FE2E2 CRC64;
MAIRCEVLLL VFLAIQLRTP STLNIKKAGN SGQVEPNNQL YDKINTKSSP QIRNPPSDAV
QRAKEVLEEI SCYPENSDAK ELKCILTRPH FMALLQTHDV VAHEVYSDEA LRVTPPPTSP
YLNGDSPESA NGDMDMENVT RVRLVQFQKN TDEPMGITLK MNELNHCIVA RIMHGGMIHR
QGTLHVGDEI REINGISVAN QTVEQLQKML REMRGSITFK IVPSYRTQSA SCERDSPSTS
RQSPANGYSS TYNSVSDLPS TTQPKGRQIY VRAQFEYDPS KDDLIPCKEA GIRFRVGEII
QIISKDDHNW WQGKLENSKN GTAGLIPSPE LQEWRVACIA MEKTKQEQQA SCTWFGKKKK
QYKDKYLAKH NAVFDQLDLV TYEEVVKLPA FRRKTLVLLG AHGVGRRHIK NTLITKHPDR
FAYPIPHTTR PARKDEENGK NYHFVSHDQM MQDISNNEYL EYGSHEDAMY GTKLETIRKI
HEQGLIAILD VEPQALKVLR TAEFAPFVVF IAAPTITPGM TEDESLQRLQ KESEILQKTY
AHYFDLTIIN NEIDETIRHL EEAIELVCTT PQWVPVSWVY
//
