ID A0A401SFY3_CHIPU Unreviewed; 329 AA.
AC A0A401SFY3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GCC29284.1};
GN ORFNames=chiPu_0007723 {ECO:0000313|EMBL:GCC29284.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC29284.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC29284.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC29284.1}.
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DR EMBL; BEZZ01000244; GCC29284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401SFY3; -.
DR STRING; 137246.A0A401SFY3; -.
DR OMA; DFLKIMM; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03156; uroplakin_I_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF216; TETRASPANIN-1; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 91..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 12..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36788 MW; B5244BE19C6E6257 CRC64;
MRIPALKAHF RDRAGPSPSL RRGRLPSHTG GRKKRSGEIR CGTRVYIRDT VGIGLLTQKS
WTETGNFRFE QNTSRLREIT KDKEKMSCFK FLKMMMFCCN CIVFLGGSAI LGVGVWVKVD
GGSFLDILAK LAPQLKQLVN VGYLCIAIGA FLVLIGFLGC YGAVKENKCM LMIFFIIVLL
IFIAQIAGAV VILAFSGLAE IFIAYIRIWA VKSIKDEYGQ SSDITTLWDT VMKEFTCCGF
DDFDDFTNSP FYNNSLNKYP KYCCKSQSHC FGDDINHSVM GCYDSLLHFL KTKTKILGIV
ALGICVLEIG AMAASMIMYC QIRKEEKSV
//
